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1623626

USP

Sucralose

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

1,6-Dichloro-1,6-dideoxy-β-D-fructofuranosyl-4-chloro-4-deoxy-α-D-galactopyranoside, E955, Trichlorosucrose

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About This Item

Empirical Formula (Hill Notation):
C12H19Cl3O8
CAS Number:
56038-13-2
Molecular Weight:
397.63
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329751159
MDL number:
MFCD03648615
Beilstein/REAXYS Number:
3654410
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grade

pharmaceutical primary standard

API family

sucralose

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

OC[C@H]1O[C@H](O[C@]2(CCl)O[C@H](CCl)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@H]1Cl

InChI

1S/C12H19Cl3O8/c13-1-4-7(17)10(20)12(3-14,22-4)23-11-9(19)8(18)6(15)5(2-16)21-11/h4-11,16-20H,1-3H2/t4-,5-,6+,7-,8+,9-,10+,11-,12+/m1/s1

InChI key

BAQAVOSOZGMPRM-QBMZZYIRSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Sucralose USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Biochem/physiol Actions

A synthetic sweet tastant detectable by humans. Activates T1R2/T1R3 sweet taste receptors on enteroendocrine cells and elicits increased hormonal secretion of glucagon-like peptide-1 and glucose-dependent insulinotrophic peptide.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

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Sucralose United States Pharmacopeia (USP) Reference Standard

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SAFC

1.00894

Sucralose

Sucralose analytical standard

Supelco

90984

Sucralose

manufacturer/tradename

USP

manufacturer/tradename

EDQM

manufacturer/tradename

-

manufacturer/tradename

-

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

grade

-

grade

analytical standard

format

neat

format

neat

format

-

format

neat

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

liquid formulation
pharmaceutical
solid formulation

application(s)

cleaning products
cosmetics
food and beverages
personal care

API family

sucralose

API family

sucralose

API family

-

API family

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

15-25°C

storage temp.

-

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Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Sucralose--an overview of the toxicity data.
H C Grice et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 38 Suppl 2, S1-S6 (2000-07-07)
Susan S Schiffman et al.
Journal of toxicology and environmental health. Part B, Critical reviews, 16(7), 399-451 (2013-11-14)
Sucralose is a synthetic organochlorine sweetener (OC) that is a common ingredient in the world's food supply. Sucralose interacts with chemosensors in the alimentary tract that play a role in sweet taste sensation and hormone secretion. In rats, sucralose ingestion
Knut Erik Tollefsen et al.
The Science of the total environment, 438, 510-516 (2012-10-04)
Sucralose (1,6-dichloro-1,6-dideoxy-b-D-fructo-furanosyl 4-chloro-4-deoxy-a-D-galactopyranoside), sold under the trade name Splenda, has been detected in municipal effluents and surface waters in the United States and Europe. The environmental presence of sucralose has led to interest in the possibility of toxic effects in
View All Related Papers

Global Trade Item Number

SKUGTIN
1623626-400MG04061838746979

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