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MART-1 (Melan A) (A103) Mouse Monoclonal Antibody

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About This Item

NACRES:

NA.41

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

A103, monoclonal

Application:

IHC (p)

Citations:

Pricing and availability is not currently available.

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Properties

biological source

mouse

Quality Level

100, 500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

A103, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (281M-84), vial of 0.5 mL concentrate (281M-85), bottle of 1.0 mL predilute (281M-87), vial of 1.0 mL concentrate (281M-86), bottle of 7.0 mL predilute (281M-88)

manufacturer/tradename

Cell Marque^®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

isotype

IgG1

control

melanoma

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic

Gene Information

human ... MLANA(2315)

Description

General description

MART-1 (also known as melan A) is a melanoma antigen recognized by T cells.1-2 MART-1 is a transmembrane protein present in melanocytes of normal skin, nevi, and most melanomas. MART-1 is a useful marker for identifying melanomas.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Analysis Note

IVD

RUO

Other Notes

For Technical Service please contact: 800-665-7284 or email: [email protected]

MART-1 Positive Control Slides, Product No. 281S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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1 of 1

This Item	281M-9	MABF3201	904H-0
Sigma-Aldrich 281M-8 MART-1 (Melan A) (A103) Mouse Monoclonal Antibody	Sigma-Aldrich 281M-9 MART-1 (Melan A) (M2-7C10) Mouse Monoclonal Antibody	Sigma-Aldrich MABF3201 Anti-MART-1/Melan-A Antibody, clone A103	Sigma-Aldrich 904H-0 HMB-45 + MART-1 (Melan A) + Tyrosinase (HMB-45 + A103 + T311) Mouse Monoclonal Antibody
species reactivity human	species reactivity human	species reactivity human	species reactivity human
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
biological source mouse	biological source mouse	biological source mouse	biological source mouse
antibody form culture supernatant	antibody form culture supernatant	antibody form purified antibody	antibody form culture supernatant
clone A103, monoclonal	clone M2-7C10, monoclonal	clone A103, monoclonal	clone HMB-45+A103+T311, monoclonal
storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C

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Expression of Melan-A and Ki-67 in desmoplastic melanoma and desmoplastic nevi.

Cynthia Kucher et al.

The American Journal of dermatopathology, 26(6), 452-457 (2004-12-25)

Desmoplastic melanoma (DMM) is an uncommon melanoma variant with a distinct morphology, including a prominent spindle cell component with fibrosis, as well as a distinct immunohistochemical profile. Histologically, the spindle cell component of DMM can be confused with sclerotic/desmoplastic nevi

Evaluation of the role of routine melan-A immunohistochemistry for exclusion of microinvasion in 120 cases of lentigo maligna.

Ravi Suchak et al.

The American Journal of dermatopathology, 36(5), 387-391 (2014-01-08)

To assess the usefulness of routine melan-A immunohistochemistry (IHC) for exclusion of microinvasion in lentigo maligna (LM). One hundred and twenty cases of LM from our archives were reviewed by 2 authors with S100 protein and melan-A IHC using a

Cloning of the gene coding for a shared human melanoma antigen recognized by autologous T cells infiltrating into tumor.

Y Kawakami et al.

Proceedings of the National Academy of Sciences of the United States of America, 91(9), 3515-3519 (1994-04-26)

By cDNA expression cloning we have isolated a gene encoding a shared human melanoma antigen recognized by HLA-A2 restricted autologous and allogenic tumor-infiltrating lymphocytes (TILs) from patients with metastatic melanoma. By using both transient and stable expression systems, transfection of

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Global Trade Item Number

SKU	GTIN
281M-85	0841683132837
281M-88	0841683132868
281M-84	0841683132820
281M-87	0841683132851
281M-86	0841683132844

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