C5013

Carboxymethylcellulose sodium salt

High viscosity

• Synonym(s): Sodium carboxymethylcellulose
• CAS Number: 9004-32-4
• UNSPSC Code: 12352201
• NACRES: NA.25
• MDL number: MFCD00081472

Properties

• biological source: wood (pulp)
• Quality Level: 200
• form: powder
• color: light yellow
• useful pH range: (20 °C, 10 g/L, 68 °F neutral)
• viscosity: 1500-3000 cP, 1 % in H₂O(25 °C)(lit.)
• mp: > 300.05 °C ((> 572.09 °F ))
• solubility: H₂O: 10 mg/mL
• cation traces: Na: 6.5-9.5%
• application(s): advanced drug delivery
• storage temp.: room temp
• SMILES string: [Na].OC(C(O)C(O)C=O)C(O)CO.OC(=O)C
• InChI: 1S/C6H12O6.C2H4O2.Na/c7-1-3(9)5(11)6(12)4(10)2-8;1-2(3)4;/h1,3-6,8-12H,2H2;1H3,(H,3,4);
• InChI key: DPXJVFZANSGRMM-UHFFFAOYSA-N

Description

General description

This product is a high viscosity carboxymethylcellulose (CMC); the viscosity of a 1% solution in water at 25 ^oC is 1500-3000 centipoise (cps). The viscosity is both concentration and temperature dependent. As the temperaure increases, the viscosity decreases. As the concentration increases, the viscosity increases.Low, medium and high viscosity CMCs are all used as suspending agents. Low viscosity CMC is usually used in ""thin"" aqueous solutions. Medium viscosity CMC is used to make solutions that look like a syrup. High viscosity CMC is used to make a mixture, which resembles a cream or lotion.

Application

Soluble carboxymethylcelluloses (CM-cellulose; CMC) available in varying viscosities are used as viscosity modifiers (thickeners) to stabilize emulsions and as a chemical dispersants of oils and other carbon structures such as nanotubes. CMCs are used in the development of biostructures such as biofilms, emulsions and nanoparticles for drug delivery.[1] Carboxymethylcellulose, high viscosity, may be used to make solutions the consistency of creams or lotions.[2]

Preparation Note

The product is soluble in water (10 mg/ml). The key to dissolving carboxymethylcellulose is to add the solid carefully to the water so that it is well dispersed (well-wetted). Adding the solid in portions may be necessary. Adding water to the dry solid produces a "clump" of solid that is very difficult to dissolve; the solid must be added to the water. Stir gently or shake intermittently; do not stir constantly with a magnetic stirring bar. High heat is not needed and may actually slow down the solubilization process. A mixing device, such as an impeller-type agitator which produces a vortex, would allow the powder to be drawn into the liquid, but it may produce some shearing. Note that this high viscosity CMC is usually used at concentrations of less than 20 mg/ml, but it is soluble in water at up to 50 mg/ml; heat is required to prepare a 50 mg/ml solution.

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)