This product can be stored tightly closed in room temperature and in dry conditions. This product does not contain an expiration date or recommended retest date. Products with no expiration date or recommended retest date should be routinely inspected by customers to ensure they perform as expected. These products are also subject to a one year warranty from the date of shipment. For more information you may access the "Product Dating Information" document under "ADDITIONAL USEFUL DOCUMENTS ABOUT OUR PRODUCTS" at the bottom of the Quality Services page with this link: https://www.sigmaaldrich.com/life-science/quality-and-regulatory-management/quality-services.
N3376
Nicotinamide
≥98% (HPLC), powder, PARP inhibitor
Synonym(s):
Niacinamide, Nicotinic acid amide, Pyridine-3-carboxylic acid amide, Vitamin B3, Vitamin PP
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About This Item
Empirical Formula (Hill Notation):
C6H6N2O
CAS Number:
Molecular Weight:
122.12
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
202-713-4
MDL number:
Beilstein/REAXYS Number:
383619
Pricing and availability is not currently available.
Product Name
Nicotinamide, ≥98% (HPLC), powder
Quality Level
assay
≥98% (HPLC)
form
powder
color
white
mp
128-131 °C (lit.)
application(s)
cell analysis
SMILES string
NC(=O)c1cccnc1
InChI
1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)
InChI key
DFPAKSUCGFBDDF-UHFFFAOYSA-N
Gene Information
human ... PARP1(142), SIRT2(22933)
Application
Used as a cofactor for certain enzymes
Biochem/physiol Actions
Nicotinamide is an amide derivative of vitamin B3 and a PARP inhibitor
Features and Benefits
This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
Preparation Note
This product can be stored tightly closed in room temperature and in dry conditions.
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This Item | |||
|---|---|---|---|
| assay ≥98% (HPLC) | assay ≥99.5% (HPLC) | assay ≥98% (HPLC) | assay ≥98.5% (HPLC) |
| form powder | form powder or crystals | form powder | form powder |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| color white | color colorless to white | color white | color colorless to white |
| application(s) cell analysis | application(s) cell analysis | application(s) - | application(s) - |
| mp 128-131 °C (lit.) | mp 128-131 °C | mp 128-131 °C (lit.) | mp 128-131 °C |
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
Storage Class
11 - Combustible Solids
flash_point_f
302.0 °F - closed cup
flash_point_c
150 °C - closed cup
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Christian W Johnson et al.
Cell reports, 28(6), 1538-1550 (2019-08-08)
Ras GTPases are mutated at codons 12, 13, and 61, with different frequencies in KRas, HRas, and NRas and in a cancer-specific manner. The G13D mutant appears in 25% of KRas-driven colorectal cancers, while observed only rarely in HRas or
Robert J Motzer et al.
The Lancet. Oncology, 14(6), 552-562 (2013-04-20)
In a phase 3 trial comparing the efficacy and safety of axitinib versus sorafenib as second-line treatment for metastatic renal cell carcinoma, patients given axitinib had a longer progression-free survival (PFS). Here, we report overall survival and updated efficacy, quality
Jordi Bruix et al.
Gut, 63(5), 844-855 (2014-02-18)
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death and is currently the main event leading to death in patients with cirrhosis. Evolving information suggests that the metabolic syndrome with non-alcoholic liver disease may be an important
Global Trade Item Number
| SKU | GTIN |
|---|---|
| N3376-500G | 04061834115984 |
| N3376-100G | 04061834115977 |
| N3376-1KG | 04061826236772 |
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Good day. I can't find storage condition and exp date. How long does N3376 stable in RT?
1 answer-
Helpful?
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