1123000

Chlorpheniramine maleate

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): (±)-Chlorpheniramine maleate salt
• Empirical Formula (Hill Notation): C₁₆H₁₉ClN₂ · C₄H₄O₄
• CAS Number: 113-92-8
• Molecular Weight: 390.86
• NACRES: NA.24
• PubChem Substance ID: 329749337
• UNSPSC Code: 41116107
• MDL number: MFCD00069225

Properties

• grade: pharmaceutical primary standard
• API family: chlorpheniramine
• manufacturer/tradename: USP
• mp: 130-135 °C (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: CN(C)CCC(C1=CC=C(Cl)C=C1)C2=NC=CC=C2.O=C(/C=C\C(O)=O)O
• InChI: 1S/C16H19ClN2.C4H4O4/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13;5-3(6)1-2-4(7)8/h3-9,11,15H,10,12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
• InChI key: DBAKFASWICGISY-BTJKTKAUSA-N
• Gene Information: human ... HRH1(3269)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Chlorpheniramine maleate USP Reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Chlorpheniramine Maleate Tablets
• Chlorpheniramine Maleate Oral Solution
• Chlorpheniramine Maleate Extended-Release Capsules
• Chlorpheniramine Maleate and Pseudoephedrine Hydrochloride Oral Solution
• Acetaminophen, Chlorpheniramine Maleate, and Dextromethorphan Hydrobromide Tablets
• Chlorpheniramine Maleate and Pseudoephedrine Hydrochloride Extended-Release Capsules
• Penicillin G Procaine, Dihydrostreptomycin Sulfate, Chlorpheniramine Maleate, and Dexamethasone Injectable Suspension

Biochem/physiol Actions

H₁ Histamine receptor antagonist.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• pcodes: P264 - P270 - P301 + P312 - P501