Skip to Content
Merck

Key Documents

View All Documentation

Skip To

U3750

Uridine

≥99%, synthetic (organic), powder

Uridine

Synonym(s):

1-β-D-Ribofuranosyluracil, Uracil-1-β-D-ribofuranoside

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Size/SKUAvailabilityPrice

About This Item

Empirical Formula (Hill Notation):
C9H12N2O6
CAS Number:
58-96-8
Molecular Weight:
244.20
NACRES:
NA.51
PubChem Substance ID:
24900640
UNSPSC Code:
41106305
EC Number:
200-407-5
MDL number:
MFCD00006526
Beilstein/REAXYS Number:
754902
Assay:
≥99%
Biological source:
synthetic (organic)
Form:
powder
Solubility:
H2O: 50 mg/mL, clear, colorless
Pricing and availability is not currently available.
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Uridine, ≥99%

biological source

synthetic (organic)

Quality Segment

200

assay

≥99%

form

powder

mp

163-167 °C (lit.)

solubility

H2O: 50 mg/mL, clear, colorless

SMILES string

OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=CC(=O)NC2=O

InChI

1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1

InChI key

DRTQHJPVMGBUCF-XVFCMESISA-N

Gene Information

mouse ... Uck1(22245)

General description

Uridine is a uracil nucleoside, specific for RNA sequence. Uridine is present in blood, seminal fluid and cerebrospinal fluid. Uridine is synthesized in living organisms by de novo and salvage pathways.

Application

Uridine has been used:
  • as a component of hippocampal neuron medium for culture of primary hippocampal neuron cells
  • in uridine rescue experiments in mouse embryonic fibroblasts and human breast cancer cells
  • in chase sequencing experiments

Biochem/physiol Actions

Uridine monophosphate is essential for protein glycosylation, polysaccharide biosynthesis and lipid metabolism. Oral administration of uridine is suggested for anisopoikilocytosis and epileptic encephalopathy disorders. Uridine has numerous biological functions like treating dry eye syndrome, regulating nervous system and favors reproduction. High levels of uridine are implicated in insulin resistance.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
U6381U30031.37607
Uridine ≥99%

Sigma-Aldrich

U3750

Uridine

Uridine BioUltra, ≥99%

Sigma-Aldrich

U6381

Uridine

Uridine powder, BioReagent, suitable for cell culture

Sigma-Aldrich

U3003

Uridine

Uridine EMPROVE® EVOLVE

SAFC

1.37607

Uridine

biological source

synthetic (organic)

biological source

synthetic (organic)

biological source

synthetic (organic)

biological source

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

400

form

powder

form

powder

form

powder

form

-

assay

≥99%

assay

≥99%

assay

≥99%

assay

-

solubility

H2O: 50 mg/mL, clear, colorless

solubility

H2O: 0.1 M, clear, colorless

solubility

H2O: 50 mg/mL

solubility

-

mp

163-167 °C (lit.)

mp

163-167 °C (lit.)

mp

163-167 °C (lit.)

mp

163-167 °C (lit.)

Still not finding the right product?

Explore all of our products under Uridine

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

1 Review This action will navigate to reviews.

Questions

1–3 of 3 Questions  

  1. What is the shelf-life of the powder?

    1 answer

    1. This product is assigned a retest date of approximately 4 years from the date of Quality release. Products that, while considered stable, may be subject to degradation over time are assigned a periodic retest date to confirm quality. The lot specific retest date is reported on the Certificate of Analysis.

      Please see the link below to review a sample or lot-specific Certificate:
      https://www.sigmaaldrich.com/product/sigma/u3750#product-documentation

      Helpful?

  2. How and for how long can I store solutions of Uridine?

    1 answer

    1. Following reconstitution, this material may be stored in aliquots at -20°C. Avoid repeated freeze/thaw cycles. Solutions prepared in water at pH 7 are stable for several days when stored refrigerated at 4 °C. The long term stability of frozen stock solutions has not been determined. In general, stock solutions stored at -20°C may be stable for several months.

      Helpful?

  3. Is this product sterile? If not, can it be filter sterilized?

    1 answer

    1. This product is not sterile. Tests and procedures can be established to ensure suitability for specific use.

      Helpful?

1 Review This action will navigate to reviews.

Reviews

Active Filters

  1. 1 Ratings-only review