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T6687

Tris Base

99-101% dry basis, crystalline, meets USP testing specifications

Synonym(s):

2-Amino-2-(hydroxymethyl)-1,3-propanediol, THAM, Tris base, Tris(hydroxymethyl)aminomethane, Trometamol, Tris

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About This Item

Empirical Formula (Hill Notation):
C4H11NO3
CAS Number:
Molecular Weight:
121.14
UNSPSC Code:
12352104
PubChem Substance ID:
NACRES:
NA.25
EC Number:
201-064-4
MDL number:
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Product Name

Tromethamine, meets USP testing specifications

agency

meets USP testing specifications

Quality Segment

assay

99-101% dry basis

form

crystalline

pH

10.0-11.5 (5%)

SMILES string

NC(CO)(CO)CO

InChI

1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2

InChI key

LENZDBCJOHFCAS-UHFFFAOYSA-N

Application


  • Preparation and Characterization of a Rifampicin Coamorphous Material with Tromethamine Coformer: An Experimental-Theoretical Study.: This research explores the preparation and characterization of a coamorphous material of rifampicin with Tromethamine, showcasing its potential in enhancing the solubility and stability of pharmaceuticals (Queiroz et al., 2024).

  • REKOVER study protocol: a prospective patient treatment registry of tramadol and dexKetoprofen trometamol oral fixed-dose combination (SKUDEXA) in moderate to severe acute pain in real-world setting in Asia.: This study involves the use of dexketoprofen trometamol in a fixed-dose combination with tramadol for managing moderate to severe acute pain, providing evidence of its effectiveness in real-world clinical settings (Ho et al., 2024).

Other Notes

Easily compare specifications for Trizma products with the Trizma specification table.

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This Item
PHR13471698002137263
assay

99-101% dry basis

assay

-

assay

-

assay

-

Quality Level

200

Quality Level

300

Quality Level

-

Quality Level

400

form

crystalline

form

-

form

-

form

powder

pH

10.0-11.5 (5%)

pH

-

pH

-

pH

-

agency

meets USP testing specifications

agency

traceable to Ph. Eur. T2550000, traceable to USP 1698002

agency

-

agency

-


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Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Related Content






Global Trade Item Number

SKUGTIN
T6687-25KG04061833445112
T6687-1KG04061838632425
T6687-10KG04061837371875
T6687-100G04061835550241
T6687-5KG04061835550258

Questions

1–3 of 3 Questions  
  1. This product says that it meets USP testing specifications. USP says to use ACS grade tromethamine. Is this product considered ACS grade?

    1 answer
    1. This is not an ACS grade Tris Base product. Please see the link below for a ACS grade Tris Base product:
      https://www.sigmaaldrich.com/product/sial/252859

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  3. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

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