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P5884

Brij® 58

average Mn ~1124

Synonym(s):

Polyethylene glycol hexadecyl ether, Polyoxyethylene (20) cetyl ether

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About This Item

Linear Formula:
HO(CH2CH2O)20C16H33
CAS Number:
UNSPSC Code:
12161900
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1899885
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description

non-ionic

Quality Segment

form

solid

mol wt

micellar avg mol wt 79,000, average Mn ~1124

aggregation number

70

technique(s)

protein quantification: suitable

CMC

0.08 mM (20-25°C)

mp

~38 °C

transition temp

cloud point >100 °C

HLB

16

SMILES string

CCCCCCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO

InChI

1S/C56H114O21/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-17-58-19-21-60-23-25-62-27-29-64-31-33-66-35-37-68-39-41-70-43-45-72-47-49-74-51-53-76-55-56-77-54-52-75-50-48-73-46-44-71-42-40-69-38-36-67-34-32-65-30-28-63-26-24-61-22-20-59-18-16-57/h57H,2-56H2,1H3

InChI key

NLMKTBGFQGKQEV-UHFFFAOYSA-N

General description

Brij 58 is a nonionic surfactant or detergent for protein extraction and permeabilization of cells. It may be used in the preparation of yeast spheroplasts.

Application

Polyethylene glycol hexadecyl ether, or Brij 58, has been used in a study to assess properties of gemini-conventional surfactant mixtures and their effects on solubilization of polycyclic aromatic hydrocarbons. It has also been used in a study to investigate RNase-sensitive constraint of bacterial nucleoid structure.

Legal Information

Brij is a registered trademark of Croda International PLC

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This Item
8.14727388831436240
technique(s)

protein quantification: suitable

technique(s)

-

technique(s)

-

technique(s)

cell culture | mammalian: suitable, protein quantification: suitable

form

solid

form

solid

form

solid

form

-

aggregation number

70

aggregation number

-

aggregation number

-

aggregation number

-

mol wt

micellar avg mol wt 79,000, average Mn ~1124

mol wt

-

mol wt

average Mn ~330

mol wt

average Mn ~1,150

mp

~38 °C

mp

38-42 °C

mp

-

mp

25-30 °C (lit.)

description

non-ionic

description

-

description

-

description

non-ionic


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pictograms

Environment

hcodes

Hazard Classifications

Aquatic Chronic 2

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

302.0 °F - closed cup

flash_point_c

150 °C - closed cup

ppe

Eyeshields, Gloves, type N95 (US)



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Macromolecular crowding can account for RNase-sensitive constraint of bacterial nucleoid structure
Foley, P., et al
Biochemical and Biophysical Research Communications, 395, 6-6 (2010)
Study of surface and solution properties of gemini-conventional surfactant mixtures and their effects on solubilization of polycyclic aromatic hydrocarbons
Panda
Journal of Molecular Liquids, 163, 6-6 (2011)
M Kellermayer et al.
Journal of cellular physiology, 159(2), 197-204 (1994-05-01)
The plasma membrane of erythrocytes, as of other cells, is thought to act as the barrier responsible for maintaining intracellular gradients of most ions and small molecular species between the cell and its environment. Controlled application of the nonionic detergent



Global Trade Item Number

SKUGTIN
P5884-500G04061834392507
P5884-1KG04061834392491
P5884-100G04061834392484

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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