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P3655

Poly-L-ornithine hydrobromide

Mol wt 30,000-70,000

Synonym(s):

L-Ornithine homopolymer hydrobromide

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About This Item

CAS Number:
UNSPSC Code:
12352209
NACRES:
NA.26
MDL number:
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Product Name

Poly-L-ornithine hydrobromide, mol wt 30,000-70,000

form

powder

Quality Level

mol wt

30,000-70,000

color

white to off-white

storage temp.

−20°C

SMILES string

[Br-].NC(CCCN)C(=O)O.[H+]

InChI

1S/C5H12N2O2.BrH/c6-3-1-2-4(7)5(8)9;/h4H,1-3,6-7H2,(H,8,9);1H

InChI key

GWRQMKDBBHFVIZ-UHFFFAOYSA-N

Application

Poly-L-ornithine hydrobromide has been used to coat coverslips in culture vessels for culturing neural progenitor cells. It has also been used to coat culture plates for culturing cerebral cells of mice.

Biochem/physiol Actions

Poly-L-ornithine is a specialized coating that acts as a charge modifier. It is a polycationic synthetic amino acid polymer. It boosts nasal absorption of hydrophilic macromolecular drugs.

Analysis Note

Molecular weight based on viscosity. Also assayed by MALLS.

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This Item
P4538P4638P0671
form

powder

form

powder

form

powder

form

powder or solid

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

color

white to off-white

color

white to off-white

color

white to off-white

color

white to off-white

mol wt

30,000-70,000

mol wt

5,000-15,000

mol wt

>100,000

mol wt

>30,000


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Related Content

Product Information Sheet


FGF2 and Insulin Signaling Converge to Regulate Cyclin D Expression in Multipotent Neural Stem Cells
Adedamola Adepoju
Stem Cell Research (2013)
Preparation and Evaluation of PEGylated Poly-L-ornithine Complex as a Novel Absorption Enhancer
Yusuke Kamiya
Biologicals : Journal of the International Association of Biological Standardization (2017)
Isolation, characterization, and differentiation of multipotent neural
progenitor cells from human cerebrospinal fluid in fetal
cystic myelomeningocele
Mario Marotta
Stem Cell Research (2017)



Global Trade Item Number

SKUGTIN
P3655-50MG04061834372745
P3655-1G04061834372721
P3655-10MG04061834372714
P3655-500MG04061834372738
P3655-100MG04061834372707

Questions

1–4 of 4 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. Can I use Poly-L-ornithine hydrobromide for coating plats in order to grow cells?

    1 answer
    1. This product is suitable for cell culture. Poly-L-ornithine hydrobromide is used for coating culture plates for cell culturing.

      Helpful?

  3. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  4. For the product P3655-100MG Poly-L-ornithine hydrobromide, which solution I should use to dilute. what condition and how long I can storage after i dilute this compound.

    1 answer
    1. This product is soluble in water up to 50 mg/mL. Solutions may be stored in aliquots at -20°C for at least 4 months. Avoid repeated freeze/thaw cycles. Please see the link below to review additional information available in the product datasheet:
      https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/167/475/p3655pis.pdf

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