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N1377

4-Nitrophenyl α-D-glucopyranoside

chromogenic, ≥99%, powder or crystals

Synonym(s):

p-Nitrophenyl α-D-glucopyranoside

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About This Item

Empirical Formula (Hill Notation):
C12H15NO8
CAS Number:
Molecular Weight:
301.25
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
223-189-3
MDL number:
Beilstein/REAXYS Number:
92212
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Product Name

4-Nitrophenyl α-D-glucopyranoside, ≥99%

Quality Segment

assay

≥99%

form

powder or crystals

solubility

methanol: 20 mg/mL, clear to very slightly hazy, colorless to greenish-yellow

storage temp.

−20°C

SMILES string

OC[C@H]1O[C@H](Oc2ccc(cc2)[N+]([O-])=O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C12H15NO8/c14-5-8-9(15)10(16)11(17)12(21-8)20-7-3-1-6(2-4-7)13(18)19/h1-4,8-12,14-17H,5H2/t8-,9-,10+,11-,12+/m1/s1

InChI key

IFBHRQDFSNCLOZ-ZIQFBCGOSA-N

Application

4-Nitrophenyl ǥ-D-glucopyranoside has been used as a substrate in an ǥ-glucosidase inhibition assay.[1][2]

Biochem/physiol Actions

4-Nitrophenyl ǥ-D-glucopyranoside serves as a substrate for glycosidases. Upon cleavage, the substrate is converted to a yellow-colored product.[3]

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This Item
N0877N7006N8759
assay

≥99%

assay

≥99% (TLC)

assay

≥98% (TLC)

assay

≥98%

solubility

methanol: 20 mg/mL, clear to very slightly hazy, colorless to greenish-yellow

solubility

methanol: 100 mg/mL, clear to very slightly hazy

solubility

water: 50 mg/mL, clear to very slightly hazy

solubility

warm ethanol: acetic acid (1:1): 20 mg/mL, clear, colorless to faintly yellow

Quality Level

300

Quality Level

200

Quality Level

300

Quality Level

100

form

powder or crystals

form

powder

form

powder

form

powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Global Trade Item Number

SKUGTIN
N1377-25G04061834108689
N1377-1G04061835557868
N1377-5G04061835557875

Questions

1–4 of 4 Questions  
  1. How is 4-Nitrophenyl α-D-glucopyranoside, Product N1377, used?

    1 answer
    1. 4-Nitrophenyl α-D-glucopyranoside is used as a substrate for the assay of α-glucosidase.  A stock solution of 4 mM is prepared in deionized water.  Upon the enzymatic hydrolysis of this substrate, 4-nitrophenol is produced.  The molar extinction coefficient of 4-nitrophenol in 0.01 M NaOH (pH 10.2) is approximately 18,380 at 400 nm.

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  2. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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  3. What is the melting point and specific rotation for 4-Nitrophenyl α-D-glucopyranoside, Product N1377?

    1 answer
    1. The melting point range from our MSDS is 209-213 °C.  The optical rotation is lot specific, and can be found on the Certificate of Analysis at our website.

      Helpful?

  4. What is the solubility of 4-Nitrophenyl α-D-glucopyranoside, Product N1377?

    1 answer
    1. We test the solubility of 4-Nitrophenyl α-D-glucopyranoside at 20 mg/mL in methanol.  When 4-Nitrophenyl α-D-glucopyranoside is used as a substrate for α-glucosidase, a 4 mM stock solution is made in water.

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