M7316

Monoamine Oxidase A human

recombinant, expressed in baculovirus infected BTI insect cells

• Synonym(s): MAO-A, MAOA
• UNSPSC Code: 12352204
• NACRES: NA.54
• EC Number: 1.4.3.4 (BRENDA, IUBMB)
• MDL number: MFCD04040932
• Recombinant: expressed in baculovirus infected BTI insect cells

Properties

• recombinant: expressed in baculovirus infected BTI insect cells
• Quality Segment: 100
• form: liquid
• packaging: vial of ~2.5 mg
• UniProt accession no.: P21397
• shipped in: dry ice
• storage temp.: −70°C
• Gene Information: human ... MAOA(4128)

Description

General description

Monoamine Oxidase A contains binding sites for 8α-S-cysteinyl-FAD. [1]

Monoamine oxidases metabolize biogenic amines in the central nervous system and the peripheral tissue. [2]

Application

Monoamine Oxidase A has been used in a study to assess abnormal behavior in a large kindred of males where a deficiency of enzymatic activity of monamine oxidase A was found. [3] It has also been used in a study to investigate an association between smoking and the inhibition of MAOA. [4]

Biochem/physiol Actions

MAO′s are proteins of the mitochondrial membrane. These enzymes are responsible for catalyzing oxidative deamination of endo- and xenobiotic amines. Substrate specificity differs for each isozyme.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)