L3791

Lamotrigine

≥98% (TLC), powder, glutamate release inhibitor

• Synonym(s): 6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diamine, GI 267119X
• Empirical Formula (Hill Notation): C₉H₇Cl₂N₅
• CAS Number: 84057-84-1
• Molecular Weight: 256.09
• NACRES: NA.77
• PubChem Substance ID: 24278792
• UNSPSC Code: 12352200
• EC Number: 281-901-8
• MDL number: MFCD00865333
• Assay: ≥98%
• Form: powder

Properties

• Product Name: Lamotrigine, ≥98%, powder
• Quality Segment: 200
• assay: ≥98%
• form: powder
• color: white
• solubility: DMSO: soluble 20 mg/mL at 60 °C, H₂O: insoluble
• originator: GlaxoSmithKline
• storage temp.: 2-8°C
• SMILES string: Nc1nnc(c(N)n1)-c2cccc(Cl)c2Cl
• InChI: 1S/C9H7Cl2N5/c10-5-3-1-2-4(6(5)11)7-8(12)14-9(13)16-15-7/h1-3H,(H4,12,13,14,16)
• InChI key: PYZRQGJRPPTADH-UHFFFAOYSA-N
• Gene Information: human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335) ; rat ... Scn2a1(24766), Scnn1a(25122)

Description

Biochem/physiol Actions

Anticonvulsant.

Features and Benefits

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety Information

• pictograms: GHS06
• signalword: Danger
• hcodes: H301
• pcodes: P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges