Skip to Content
Merck

Key Documents

View All Documentation

Skip To

41639

Dimethyl sulfoxide

BioUltra, Molecular Biology, ≥99.5% (GC)

Synonym(s):

DMSO

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View
Pack SizeSKUAvailabilityPrice

About This Item

Linear Formula:
(CH3)2SO
CAS Number:
67-68-5
Molecular Weight:
78.13
UNSPSC Code:
12191502
NACRES:
NA.25
PubChem Substance ID:
57650076
EC Number:
200-664-3
Beilstein/REAXYS Number:
506008
MDL number:
MFCD00002089
Assay:
≥99.5% (GC)
Grade:
Molecular Biology
Technique(s):
GC/GC: suitable
Bp:
189 °C (lit.)
Vapor pressure:
0.42 mmHg ( 20 °C)
Pricing and availability is not currently available.
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

grade

Molecular Biology

Quality Level

200

vapor density

2.7 (vs air)

vapor pressure

0.42 mmHg ( 20 °C)

product line

BioUltra

assay

≥99.5% (GC)

form

liquid

autoignition temp.

573 °F

expl. lim.

42 %, 63 °F

technique(s)

GC/GC: suitable

impurities

Dnases, none detected, RNases, none detected, insoluble matter, passes filter test, phosphatases, none detected, proteases, none detected, ≤0.001% free acid (as CH3COOH)

evapn. residue

≤0.005%

color

colorless

refractive index

n20/D 1.479

bp

189 °C (lit.)

mp

16-19 °C (lit.)

solubility

H2O: miscible (completely)

density

1.10 g/mL (lit.)

SMILES string

CS(C)=O

cation traces

Al: ≤0.5 mg/kg, Ba: ≤0.1 mg/kg, Bi: ≤0.1 mg/kg, Ca: ≤0.5 mg/kg, Cd: ≤0.05 mg/kg, Co: ≤0.02 mg/kg, Cr: ≤0.02 mg/kg, Cu: ≤0.02 mg/kg, Fe: ≤0.5 mg/kg, K: ≤0.5 mg/kg, Li: ≤0.1 mg/kg, Mg: ≤0.1 mg/kg, Mn: ≤0.02 mg/kg, Mo: ≤0.1 mg/kg, Na: ≤1 mg/kg, Ni: ≤0.5 mg/kg, Pb: ≤0.1 mg/kg, Sr: ≤0.1 mg/kg, Zn: ≤0.1 mg/kg

λ

neat

UV absorption

λ: 280 nm Amax: 0.22

suitability

suitable for molecular biology

InChI

1S/C2H6OS/c1-4(2)3/h1-2H3

InChI key

IAZDPXIOMUYVGZ-UHFFFAOYSA-N

General description

Dimethyl sulfoxide (DMSO) is an effective aprotic solvent. It is colorless, odorless and hygroscopic in nature. DMSO enhance the permeability of various hydrophilic and lipophilic permeants. It is one of the widely used solvents in the laboratory.

Application

Dimethyl sulfoxide (DMSO) has been used as a vehicle for test compounds in various experimental studies.[1] It has also been used as a solvent during amyloid β (Aβ) aggregation protocol for resolubilization of peptide to maintain its dissociated state.

Other Notes

Polybrene / DMSO-assisted gene transfer[2]

Disclaimer

Supercools easily and remelts slowly at room temperature. Solidified product can be re-liquified by warming to room temperature without detriment to the product.

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item
D8418D2438PHR1309
Dimethyl sulfoxide BioUltra, Molecular Biology, ≥99.5% (GC)

Sigma-Aldrich

41639

Dimethyl sulfoxide

Dimethyl sulfoxide Molecular Biology

Sigma-Aldrich

D8418

Dimethyl sulfoxide

Dimethyl sulfoxide sterile-filtered, BioPerformance Certified, meets EP, USP testing specifications, suitable for hybridoma

Sigma-Aldrich

D2438

Dimethyl sulfoxide

Dimethyl Sulfoxide Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1309

Dimethyl Sulfoxide

assay

≥99.5% (GC)

assay

≥99.9%

assay

-

assay

-

Quality Level

200

Quality Level

200

Quality Level

400

Quality Level

300

grade

Molecular Biology

grade

Molecular Biology

grade

BioPerformance Certified

grade

certified reference material, pharmaceutical secondary standard

technique(s)

GC/GC: suitable

technique(s)

DNA sequencing: suitable, PCR: suitable, transfection: suitable

technique(s)

cell culture | hybridoma: suitable, cryopreservation: suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

solubility

H2O: miscible (completely)

solubility

H2O: miscible (completely)

solubility

H2O: miscible (completely)

solubility

-

form

liquid

form

liquid

form

liquid

form

-

Still not finding the right product?

Explore all of our products under Dimethyl sulfoxide

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

188.6 °F - closed cup

flash_point_c

87 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCP1830
BCCM8451
BCCM1815
BCCL0999
BCCL9737

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Amyloid beta oligomers induce neuronal elasticity changes in age-dependent manner: a force spectroscopy study on living hippocampal neurons
Ungureanu A, et al.
Scientific reports, 6, 25841-25841 (2016)
The use of dimethylsulfoxide as a vehicle in cell culture experiments using ovarian carcinoma cell lines
Rodriguez-Burford C, et al.
Biotechniques, 78(1), 17-21 (2003)
Topical and Transdermal Drug Delivery
Handbook of non-invasive drug delivery systems: science and technology (2009)
View All Related Papers

Global Trade Item Number

SKUGTIN
667056-1G04061826699812
41639-100ML04061832089645
41639-500ML04061832089652

Questions

1–10 of 11 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. Is Dimethyl sulfoxide a sterile product?

    1 answer

    1. No, this product is not considered sterile.  Product Nos. D2560 and D2438 are sterile-filtered.

      Helpful?

  4. What is the molarity of DMSO?

    1 answer

    1. DMSO will have a molarity of 14.1M, based on a density of 1.1 g/mL and a molecular weight of 78.13 g/mol.

      Helpful?

  5. Where does DMSO come from?

    1 answer

    1. DMSO is known to have been isolated from tree bark in the past. It is now a commericially synthesized solvent.

      Helpful?

  6. What is Sure/Seal™ packaging?

    1 answer

    1. The Aldrich Sure/Seal™ packaging system is useful in the handling and storage of air-sensitive reagents.

      Helpful?

  7. Dimethyl sulfoxide (DMSO) should be a liquid.  Why did it arrive as a solid?

    1 answer

    1. DMSO supercools easily, and re-melts slowly at room temperature. The melting point is 16-19 °C. The solidified product can be re-liquefied by warming to room temperature without detriment to the product.

      Helpful?

  8. What is the DMSO dissolved in?

    1 answer

    1. DMSO is not dissolved in any solvent. It is a pure chemical compound that is a liquid at room temperature.

      Helpful?

  9. Does DMSO have any synthetic utility?

    1 answer

    1. DMSO has been used to oxidize thiols and disulfides to sulfonic acids, hydrolysis of epoxides, thioalkylation of phenols, and oxidation of primary alcohols and halides, and esters of primary alcohols to aldehydes.

      Helpful?

  10. What is the Department of Transportation shipping information for this product?

    1 answer

    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

1–10 of 11 Questions  

Reviews

No rating value

Active Filters