MAB354

Anti-SST Antibody

CHEMICON^®, rat monoclonal, YC7

• Synonym(s): Anti-Somatostatin
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41
• Clone: YC7, monoclonal
• Species reactivity: rabbit, rat, human
• Application: IHC
• Citations: 334

Properties

• Product Name: Anti-Somatostatin Antibody, clone YC7, culture supernatant, clone YC7, Chemicon^®
• biological source: rat
• Quality Level: 100
• antibody form: culture supernatant
• antibody product type: primary antibodies
• clone: YC7, monoclonal
• species reactivity: rabbit, rat, human
• manufacturer/tradename: Chemicon^®
• technique(s): immunohistochemistry: suitable
• isotype: IgG2b
• NCBI accession no.: NM_001048.3
• UniProt accession no.: P61278
• shipped in: dry ice
• target post-translational modification: unmodified
• Gene Information: human ... SST(6750)

Description

General description

Somatostatin (also known as growth hormone inhibiting hormone (GHIH) or somatotropin release-inhibiting factor (SRIF) has two active forms, 14 amino acids and 28 amino acids, which are produced by alternate cleavage of the single preproprotein. Somatostatin is expressed widely and acts to inhibit the release of several secondary hormones by binding to high-affinity G-protein coupled somatostatin receptors. Presence of somatostatin has been shown in sympathetic nerves, mucosal cells, myenteric nerves of the gastrointestinal tract, salivary glands and in some parafollicular cells of the thyroid.

Immunogen

Synthetic peptide corresponding to amino acids 1-14 of cyclic somatostatin conjugated to bovine thyroglobulin using carbodiimide.

Application

Anti-Somatostatin Antibody, clone YC7 is an antibody against Somatostatin for use in IH.

Immunohistochemistry at 1:50-1:100 on human brain.

Optimal working dilutions must be determined by the end user.

Biochem/physiol Actions

Anti-SST, clone YC7 recognizes Somatostatin. Shows no cross-reactivity to enkephalins, other endorphins, substance P or CGRP. Partially cross-reacts with somatostatin fragments.

Physical form

Lyophilized Supernatant, preservative free.

Preparation Note

Lyophilized antibody can be kept at 2-8°C for up to 3 months and should be kept at -20°C for long term storage. Reconstitute with 100μL sterile DI water. Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

Analysis Note

Control
Pancreas, Brain

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319
• pcodes: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2
• Storage Class: 11 - Combustible Solids