Key Documents

Vinorelbine ditartrate salt hydrate

Name: Vinorelbine ditartrate salt hydrate
Brand: SIGMA

≥98% (HPLC), powder

Synonym(s):

3′,4′-Didehydro-4′-deoxy-C′-norvincaleukoblastine [R-(R*,R*)-2-3-dihydroxybutanedioate (1:2)salt], 5′-Noranhydrovinoblastine tartrate, KW-2307, NVB, Navelbine tartrate

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About This Item

Empirical Formula (Hill Notation):

C₄₅H₅₄N₄O₈ · 2C₄H₆O₆ · xH₂O

CAS Number:

125317-39-7

Molecular Weight:

1079.11 (anhydrous basis)

NACRES:

NA.77

PubChem Substance ID:

24724660

UNSPSC Code:

12352200

MDL number:

MFCD03613607

Assay:

≥98% (HPLC)

Form:

powder

Pricing and availability is not currently available.

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Properties

Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

off-white

solubility

H₂O: 10 mg/mL

originator

Pierre Fabre

shipped in

wet ice

storage temp.

2-8°C

SMILES string

[H]O[H].O[C@H]([C@@H](O)C(O)=O)C(O)=O.O[C@H]([C@@H](O)C(O)=O)C(O)=O.[H][C@]12C[N@H](CC(CC)=C1)Cc3c([nH]c4ccccc34)[C@@](C2)(C(=O)OC)c5cc6c(cc5OC)N(C)[C@@]7([H])[C@](O)([C@H](OC(C)=O)[C@]8(CC)C=CCN9CC[C@]67[C@]89[H])C(=O)OC

InChI

1S/C45H54N4O8.2C4H6O6.H2O/c1-8-27-19-28-22-44(40(51)55-6,36-30(25-48(23-27)24-28)29-13-10-11-14-33(29)46-36)32-20-31-34(21-35(32)54-5)47(4)38-43(31)16-18-49-17-12-15-42(9-2,37(43)49)39(57-26(3)50)45(38,53)41(52)56-7;2*5-1(3(7)8)2(6)4(9)10;/h10-15,19-21,28,37-39,46,53H,8-9,16-18,22-25H2,1-7H3;2*1-2,5-6H,(H,7,8)(H,9,10);1H2/t28-,37-,38+,39+,42+,43+,44-,45-;2*1-,2-;/m011./s1

InChI key

ZLIPKSVXTCRHIB-GNBHHJMASA-N

Description

Biochem/physiol Actions

Potent anti-mitotic, anti-tumor agent; inhibits microtubule assembly.

Vinorelbine is a potent anti-mitotic, anti-tumor agent. Vinorelbine inhibits microtubule assembly. Low neurotoxicity is related to its higher affinity for mitotic microtubules than for axonal microtubules.

Features and Benefits

This compound was developed by Pierre Fabre. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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Show Differences

1 of 1

This Item	A2846	SML1229	B3313
Sigma-Aldrich V2264 Vinorelbine ditartrate salt hydrate	Sigma-Aldrich A2846 A-134974 dihydrochloride hydrate	Sigma-Aldrich SML1229 2′,3′-cGAMP sodium salt	Sigma-Aldrich B3313 Bicyclol
form powder	form solid	form powder	form powder
assay ≥98% (HPLC)	assay ≥98% (HPLC)	assay ≥98% (HPLC)	assay ≥98% (HPLC)
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
storage temp. 2-8°C	storage temp. -	storage temp. −20°C	storage temp. 2-8°C
solubility H₂O: 10 mg/mL	solubility H₂O: soluble	solubility -	solubility DMSO: >10 mg/mL
originator Pierre Fabre	originator Abbott	originator -	originator -

pictograms

GHS07

signalword

Warning

hcodes

H317

pcodes

P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364

Hazard Classifications

Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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