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A6412

Aflatoxin M1–BSA Conjugate

Mycotoxin, powder

Synonym(s):

AFM1-BSA conjugate

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About This Item

UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Form:
powder
Quality level:
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Product Name

Aflatoxin M1–BSA Conjugate,

form

powder

Quality Level

extent of labeling

4-8 mol aflatoxin M1 per mol BSA (Lowry)

storage temp.

2-8°C

General description

Aflatoxin M1 is a hydroxylated metabolite ofaflatoxin B1. It is found in milk secreted by mammary glands of lactatinganimals, humans, and milk products.

Application

Aflatoxin M1–BSA Conjugate has been used in the indirect competitive enzyme-linked immunosorbent assay (ic-ELISA) with non-labeled aflatoxin M1 and anti-AFM1 antibody.[1]

Biochem/physiol Actions

Aflatoxin M1 is a mycotoxin that elicits both hepatotoxic[2] and hepatocarcinogenic effects leading to immunosuppression in animals.[3] The bioconjugate of aflatoxin M1 (AFM1) with bovine serum albumin (BSA) is useful in the generation of AFM1 specific antibodies which may have immunoassay applications.[2]

Disclaimer

Possibly carcinogenic.

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D0565A6428123850
form

powder

form

lyophilized powder

form

film

form

solid

Quality Level

200

Quality Level

-

Quality Level

200

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

extent of labeling

4-8 mol aflatoxin M1 per mol BSA (Lowry)

extent of labeling

~10 mol Digoxin per mol albumin

extent of labeling

-

extent of labeling

-


pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Carc. 1B

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges



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K Thirumala-Devi et al.
Journal of agricultural and food chemistry, 50(4), 933-937 (2002-02-07)
High-titer rabbit polyclonal antibodies to aflatoxin M(1) (AFM1) were produced by utilizing AFM1-bovine serum albumin (BSA) conjugate as an immunogen. An indirect competitive enzyme-linked immunosorbent assay was standardized for estimating AFM1 in milk and milk products. To avoid the influence
Fatemeh Khademi et al.
Jundishapur journal of microbiology, 8(4), e16850-e16850 (2015-06-03)
Aflatoxins are the most extensively studied group of mycotoxins produced by molds, especially the Aspergillus group, which are highly toxic to animals and humans. Since immunoassay is a simple and rapid method for the analysis of many toxic substances in
Aflatoxin M1 in milk and dairy products, occurrence and recent challenges: A review
Iqbal S Z, et al.
Trends in Food Science & Technology, 46 (1) (2015)



Global Trade Item Number

SKUGTIN
A6412-1MG04061833382202

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