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DL-2-Aminoadipic acid

Name: <SC>DL</SC>-2-Aminoadipic acid
Brand: SIGMA

≥99% (TLC), powder, gliotoxic

Synonym(s):

DL-α-Aminoadipic acid

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About This Item

Linear Formula:

HO₂C(CH₂)₃CH(NH₂)CO₂H

CAS Number:

542-32-5

Molecular Weight:

161.16

NACRES:

NA.32

PubChem Substance ID:

24890441

UNSPSC Code:

12352106

EC Number:

208-809-2

MDL number:

MFCD00063119

Assay:

≥99%

Form:

powder

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Properties

Product Name

DL-2-Aminoadipic acid, ≥99%

Quality Segment

200

assay

≥99%

form

powder

mp

196-198 °C (lit.)

storage temp.

2-8°C

SMILES string

NC(CCCC(O)=O)C(O)=O

InChI

1S/C6H11NO4/c7-4(6(10)11)2-1-3-5(8)9/h4H,1-3,7H2,(H,8,9)(H,10,11)

InChI key

OYIFNHCXNCRBQI-UHFFFAOYSA-N

Gene Information

rat ... Grin2b(24410)

Description

Application

DL-2-Aminoadipic acid (AAA) has been used as an astrotoxin to kill astrocytes that prevent efficient integration of transplanted cells into the retina. It has also been used as a gliotoxin to study the effect of astrocytic swelling on the tortuosity.

Biochem/physiol Actions

DL-2-Aminoadipic acid (AAA) is a six-carbon homolog of glutamate and a gliotoxic compound. It is generally used to considerably reduce the number of astroglia in cerebellar cultures that acts as a model to study the mechanisms of a-aminoadipic acid induced glial toxicity.

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This Item	217700	92591	H3648
Sigma-Aldrich A0637 DL-2-Aminoadipic acid	Sigma-Aldrich 217700 DL-2-Aminocaprylic acid	Sigma-Aldrich 92591 DL-2,6-Diaminopimelic acid	Sigma-Aldrich H3648 (±)-3-Hydroxydecanoic acid
assay ≥99%	assay 99%	assay ≥95% (TLC)	assay ≥98%
form powder	form solid	form powder	form powder
Quality Level 200	Quality Level 100	Quality Level 100	Quality Level 200
storage temp. 2-8°C	storage temp. -	storage temp. -	storage temp. 2-8°C
Gene Information rat ... Grin2b(24410)	Gene Information -	Gene Information -	Gene Information -
mp 196-198 °C (lit.)	mp 260 °C (dec.) (lit.)	mp -	mp -