14300

Betaine monohydrate

≥99.0% (NT)

• Synonym(s): 1-carboxy-n,n,n-trimethylmethanaminium hydroxide, 2-(trimethylammonio)acetate hydrate, glycine betaine hydrate
• Linear Formula: (CH₃)₃N⁺CH₂COO^- · H₂O
• CAS Number: 590-47-6
• Molecular Weight: 135.16
• Beilstein: 3626258
• EC Number: 203-490-6
• MDL number: MFCD00150010
• UNSPSC Code: 51171529
• PubChem Substance ID: 57647146
• NACRES: NA.25

Properties

• Assay: ≥99.0% (NT)
• form: solid
• solubility: H₂O: 0.1 g/mL, clear, colorless
• storage temp.: 2-8°C
• SMILES string: O.C[N+](C)(C)CC([O-])=O
• InChI: 1S/C5H11NO2.H2O/c1-6(2,3)4-5(7)8;/h4H2,1-3H3;1H2
• InChI key: NJZRLXNBGZBREL-UHFFFAOYSA-N

Description

Application

Betaine monohydrate:

• is suitable for use to improve the PCR amplification of GC-rich DNA sequences by reducing the formation of secondary structure caused by GC-rich regions
• is suitable for use as a component of PCR reaction mixture
• is suitable for use in a study to identify yield enhancers of PCR
• has been used to study nitrogen balance and nutrient digestibility in piglets fed diets deficient in methionine and low in compatible osmolytes
• has also been used to compare the effects of pressure on three layered hydrates

Biochem/physiol Actions

End-product of oxidative metabolism of choline, betaine is a general methyl donor, in particular in a minor pathway of methionine biosynthesis. It is used to treat homocystinuria, which is a defect in the major pathway of methionine biosynthesis.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves