If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
60010
Kaempferol
≥97.0% (HPLC)
Synonym(s):
3,4′,5,7-Tetrahydroxyflavone, 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, Robigenin
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| Size/SKU | Availability | Price |
|---|
About This Item
Quality Segment
assay
≥97.0% (HPLC)
impurities
≤12% water
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
SMILES string
Oc1ccc(cc1)C2=C(O)C(=O)c3c(O)cc(O)cc3O2
InChI
1S/C15H10O6/c16-8-3-1-7(2-4-8)15-14(20)13(19)12-10(18)5-9(17)6-11(12)21-15/h1-6,16-18,20H
InChI key
IYRMWMYZSQPJKC-UHFFFAOYSA-N
Gene Information
human ... CDC2(983), CDK5(1020), CDK6(1021), CYP1A2(1544), CYP2C9(1559), GSK3A(2931)
mouse ... Hexa(15211)
General description
Application
- to test its effect on osteoblast proliferation, migration, and differentiation in mouse pre-osteoblast cell line (MC3T3-E1 cells)[3]
- as an antioxidant and a hepatoprotective agent against zearalenone (ZEA)-induced oxidative stress and apoptosis in HEPG2 cells[4]
- as a neuroprotective agent against cadmium chloride (CdCl2) induced hippocampal damage and memory deficits in rats
- as an anti-inflammatory agent, together with apigenin, for stem-cell therapy on knee osteoarthritic male rats[5]
Biochem/physiol Actions
1 of 1
This Item | |||
|---|---|---|---|
| assay ≥97.0% (HPLC) | assay ≥90% (HPLC) | assay ≥99.0% (HPLC) | assay - |
| application(s) metabolomics | application(s) - | application(s) food and beverages | application(s) pharmaceutical (small molecule) |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level - |
| impurities ≤12% water | impurities - | impurities - | impurities - |
| Gene Information human ... CDC2(983), CDK5(1020), CDK6(1021), CYP1A2(1544), CYP2C9(1559), GSK3A(2931) | Gene Information human ... CDC2(983), CDK5(1020), CDK6(1021), CYP1A2(1544), CYP2C9(1559), GSK3A(2931) | Gene Information - | Gene Information - |
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signalword
Warning
Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
hcodes
Hazard Classifications
Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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