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Dextromethorphan hydrobromide

Name: Dextromethorphan hydrobromide
Brand: SIAL

meets USP testing specifications

Synonym(s):

Dextromethorphan hydrobromide monohydrate, (9S,13S,14S)-3-Methoxy-17-methylmorphinan hydrobromide

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About This Item

Empirical Formula (Hill Notation):

C₁₈H₂₅NO · HBr · H₂O

CAS Number:

6700-34-1

Molecular Weight:

370.32

UNSPSC Code:

41116107

NACRES:

NA.21

PubChem Substance ID:

24894320

MDL number:

MFCD02173901

Beilstein/REAXYS Number:

6453793

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Properties

Quality Level

200

agency

USP/NF, meets USP testing specifications

assay

98.0-102.0% anhydrous basis

form

solid

SMILES string

Br[H].[H]O[H].[H][C@]12CCCC[C@]13CCN(C)[C@H]2Cc4ccc(OC)cc34

InChI

1S/C18H25NO.BrH.H2O/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18;;/h6-7,12,15,17H,3-5,8-11H2,1-2H3;1H;1H2/t15-,17+,18+;;/m1../s1

InChI key

STTADZBLEUMJRG-IKNOHUQMSA-N

Gene Information

human ... GRIN2A(2903), SIGMAR1(10280)

Description

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This Item	1181007	PHR1018	Y0002402
Sigma-Aldrich D9684 Dextromethorphan hydrobromide	USP 1181007 Dextromethorphan hydrobromide	Supelco PHR1018 Dextromethorphan HBr	Y0002402 Dextromethorphan for system suitability CRS
assay 98.0-102.0% anhydrous basis	assay -	assay -	assay -
Quality Level 200	Quality Level -	Quality Level 300	Quality Level -
form solid	form -	form -	form -
agency USP/NF, meets USP testing specifications	agency -	agency traceable to Ph. Eur. D0740000, traceable to USP 1181007	agency -
Gene Information human ... GRIN2A(2903), SIGMAR1(10280)	Gene Information human ... GRIN2A(2903), SIGMAR1(10280)	Gene Information human ... GRIN2A(2903), SIGMAR1(10280)	Gene Information -

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pictograms

GHS06,GHS09

signalword

Danger

hcodes

H301,H411

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Chronic 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

pcodes

P264 - P273 - P301 + P310 - P391 - P405 - P501

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Dextromethorphan attenuates LPS-induced adhesion molecule expression in human endothelial cells.

Shinn-Jong Jiang et al.

Microcirculation (New York, N.Y. : 1994), 20(2), 190-201 (2012-11-13)

This study examines the effect of Dextromethorphan (d-3-methoxy-17-methylmorphinan; DXM), a commonly used cough-suppressing drug, on the expression of VCAM-1 and ICAM-1 in human umbilical vein endothelial cells (HUVECs) stimulated with lipopolysaccharide (LPS). The effect of DXM on expression of cell

[Dextromethorphan (DXM): new methods of intoxications among teenagers--a case description].

Ewa Tomczak et al.

Archiwum medycyny sadowej i kryminologii, 62(3), 197-202 (2013-05-09)

The study highlighted the problem of intoxication using substances and/or preparations, to which nowadays young people have unrestricted access. Based on the case developed in the Department of Forensic Medicine of the Medical University of Gdansk, our team members were

Fixed drug eruption due to dextromethorphan with tolerance to other opioids.

G Davila-Fernández et al.

Journal of investigational allergology & clinical immunology, 23(4), 281-282 (2013-08-24)