1173508

Desoximetasone

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): 9-Fluoro-11β,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione
• Empirical Formula (Hill Notation): C₂₂H₂₉FO₄
• CAS Number: 382-67-2
• Molecular Weight: 376.46
• UNSPSC Code: 41116107
• NACRES: NA.24
• MDL number: MFCD00083301

Properties

• biological source: synthetic
• grade: pharmaceutical primary standard
• agency: USP
• vapor pressure: <0.0000001 kPa ( 25 °C)
• API family: desoximetasone
• form: powder
• packaging: pkg of 200 mg
• manufacturer/tradename: USP
• storage condition: protect from light
• color: white
• solubility: acetone: freely soluble, alcohol: freely soluble, benzene: slightly soluble, chloroform: freely soluble, ether: slightly soluble, water: insoluble
• application(s): pharmaceutical (small molecule)
• SMILES string: [H][C@@]12C[C@@H](C)[C@H](C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]3(F)[C@@]2([H])CCC4=CC(=O)C=C[C@]34C
• InChI: 1S/C22H29FO4/c1-12-8-16-15-5-4-13-9-14(25)6-7-21(13,3)22(15,23)18(27)10-20(16,2)19(12)17(26)11-24/h6-7,9,12,15-16,18-19,24,27H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,18+,19-,20+,21+,22+/m1/s1
• InChI key: VWVSBHGCDBMOOT-IIEHVVJPSA-N
• Gene Information: human ... NR3C1(2908)

Description

General description

Desoximetasone is a topical corticosteroid known to modify the functions of leukocytes that are mainly responsible for skin infections, inflammation and allergies.

Application

Desoximetasone USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Desoximetasone Cream
• Desoximetasone Gel
• Desoximetasone Ointment
• Dexamethasone

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• pictograms: GHS08,GHS07
• signalword: Warning
• hcodes: H302,H317,H361d
• pcodes: P202 - P261 - P280 - P301 + P312 - P302 + P352 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Repr. 2 - Skin Sens. 1
• Storage Class: 11 - Combustible Solids
• flash_point_f: Not applicable
• flash_point_c: Not applicable