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1085003

USP

Caffeine

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

1H-Purine-2,6-dione, 1,3,7-Trimethylxanthine

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About This Item

Empirical Formula (Hill Notation):
C8H10N4O2
CAS Number:
Molecular Weight:
194.19
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
17705
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grade

pharmaceutical primary standard

API family

pentoxifylline, caffeine, dimenhydrinate

manufacturer/tradename

USP

mp

234-236.5 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

CN1C(=O)N(C)c2ncn(C)c2C1=O

InChI

1S/C8H10N4O2/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2/h4H,1-3H3

InChI key

RYYVLZVUVIJVGH-UHFFFAOYSA-N

Gene Information

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Caffeine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Caffeine Citrate Injection
  • Caffeine Citrate Oral Solution
  • Acetaminophen and Caffeine Tablets
  • Ergotamine Tartrate and Caffeine Tablets
  • Butalbital, Aspirin, and Caffeine Capsules
  • Ergotamine Tartrate and Caffeine Suppositories

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

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This Item
C0100000BP766PHR1009
Caffeine British Pharmacopoeia (BP) Reference Standard

BP766

Caffeine

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

grade

certified reference material, pharmaceutical secondary standard

manufacturer/tradename

USP

manufacturer/tradename

EDQM

manufacturer/tradename

BP

manufacturer/tradename

-

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical
pharmaceutical small molecule

application(s)

pharmaceutical (small molecule)

format

neat

format

neat

format

neat

format

neat

mp

234-236.5 °C (lit.)

mp

234-236.5 °C (lit.)

mp

234-236.5 °C (lit.)

mp

234-236.5 °C (lit.)

Gene Information

human ... ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140)

Gene Information

human ... ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140)

Gene Information

human ... ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140)

Gene Information

human ... ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140)


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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

flash_point_f

Not applicable

flash_point_c

Not applicable

Storage Class

11 - Combustible Solids



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Certificates of Analysis (COA)

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Quantitative reversed-phase high-performance liquid chromatographic analysis of ampicillin
Margosis M, et al.
Journal of Chromatography A, 236(2), 461-468 (1982)
Caffeine Citrate Oral Solution
United States Pharmacopeia, 30(5), 663-663 (2013)
Acetaminophen and Caffeine Tablets
United States Pharmacopeia, 41(2), 51-51 (2020)



Global Trade Item Number

SKUGTIN
1085003-200MG04061838686138

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

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