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V4015

Verbascoside

≥99% (HPLC)

Synonym(s):

Acetoside, Kusaginin

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About This Item

Empirical Formula (Hill Notation):
C29H36O15
CAS Number:
61276-17-3
Molecular Weight:
624.59
NACRES:
NA.25
PubChem Substance ID:
329829047
UNSPSC Code:
12352200
MDL number:
MFCD00221751
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Quality Level

200

assay

≥99% (HPLC)

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

room temp

SMILES string

C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](OCCc3ccc(O)c(O)c3)O[C@H](CO)[C@H]2OC(=O)\C=C\c4ccc(O)c(O)c4)[C@H](O)[C@H](O)[C@H]1O

InChI

1S/C29H36O15/c1-13-22(36)23(37)24(38)29(41-13)44-27-25(39)28(40-9-8-15-3-6-17(32)19(34)11-15)42-20(12-30)26(27)43-21(35)7-4-14-2-5-16(31)18(33)10-14/h2-7,10-11,13,20,22-34,36-39H,8-9,12H2,1H3/b7-4+/t13-,20+,22-,23+,24+,25+,26+,27+,28+,29-/m0/s1

InChI key

FBSKJMQYURKNSU-ZLSOWSIRSA-N

General description

Verbascoside, also known as acteoside, is a hydrophilic plant compound first isolated from mullein (Verbascum sinuatum L.).[1] The chemical structure of verbascoside comprises hydroxyphenylethyl and cinnamic acid moieties bound to a β-glucopyranose via a glycosidic bond.[1]

Application

Verbascoside has been used:
  • as a reference standard for high-performance liquid chromatography (HPLC) analysis[2]
  • as a reference standard for detection of phenolic compounds in olive mill wastewater and pomace by high-performance liquid chromatography (HPLC)-diode-array detector (DAD)-qTOF system[3]
  • to test its anti-viral activity against respiratory syncytial virus (RSV) in HEP2 cells and A549 cells[4]

Biochem/physiol Actions

Phenylethanoid glycoside. Antioxidant and antiproliferative.
Verbascoside has anti-inflammatory and photoprotective properties.[5] It has shown neuroprotective effects on PC12 neuronal cells against neurotoxicity.[6] Verbascoside is proven to be a potent inhibitor of xanthine oxidase (XOD) in in vitro studies.[7]

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This Item
00820580PHL892891711455
Verbascoside ≥99% (HPLC)

Sigma-Aldrich

V4015

Verbascoside

Verbascoside primary reference standard

00820580

Verbascoside

Verbascoside phyproof® Reference Substance

PHL89289

Verbascoside

Verbascoside United States Pharmacopeia (USP) Reference Standard

USP

1711455

Verbascoside

assay

≥99% (HPLC)

assay

-

assay

≥90.0% (HPLC)

assay

-

Quality Level

200

Quality Level

-

Quality Level

-

Quality Level

-

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

application(s)

-

application(s)

-

application(s)

pharmaceutical

storage temp.

room temp

storage temp.

-

storage temp.

-

storage temp.

-

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Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
SLCP4923
SLCQ1161
SLCP8197
SLCP7825
SLCD6521

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Kiramage Chathuranga et al.
Viruses, 11(7) (2019-07-07)
The herbs Plantago asiatica and Clerodendrum trichotomum have been commonly used for centuries in indigenous and folk medicine in tropical and subtropical regions of the world. In this study, we show that extracts from these herbs have antiviral effects against
Guo-Qing Sheng et al.
European journal of pharmacology, 451(2), 119-124 (2002-09-17)
The neuroprotective effects of verbascoside, one of phenylpropanoid glucoside isolated from the Chinese herbal medicine Buddleja officinalis Maxim, on 1-methyl-4-phenylpyridinium ion (MPP(+)) induced apoptosis and oxidative stress in PC12 neuronal cells were investigated. Treatment of PC12 cells with MPP(+) for
Kalina Alipieva et al.
Biotechnology advances, 32(6), 1065-1076 (2014-07-23)
Phenylethanoid glycosides are naturally occurring water-soluble compounds with remarkable biological properties that are widely distributed in the plant kingdom. Verbascoside is a phenylethanoid glycoside that was first isolated from mullein but is also found in several other plant species. It
View All Related Papers

Global Trade Item Number

SKUGTIN
V4015-10MG04061832402567

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