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U5252

Uridine 5′-diphospho-N-acetylgalactosamine disodium salt

≥97%, synthetic (organic), powder

Synonym(s):

(UDP)-GalNAc, UDP-GalNAc, UDP-N-acetylgalactosamine, Uridine[5′]diphospho[1](2-acetamino-2-deoxy-α-D-galactopyranose) disodium salt

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About This Item

Empirical Formula (Hill Notation):
C17H25N3Na2O17P2
CAS Number:
Molecular Weight:
651.32
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
MDL number:
Beilstein/REAXYS Number:
5375867
Assay:
≥97%
Biological source:
synthetic (organic)
Form:
powder
Solubility:
water: 50 mg/mL, clear, colorless
Storage temp.:
−20°C
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Product Name

Uridine 5′-diphospho-N-acetylgalactosamine disodium salt, ≥97%

biological source

synthetic (organic)

Quality Level

assay

≥97%

form

powder

solubility

water: 50 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

[Na+].[Na+].CC(=O)N[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1OP([O-])(=O)OP([O-])(=O)OC[C@H]2OC([C@H](O)[C@@H]2O)N3C=CC(=O)NC3=O

InChI

1S/C17H27N3O17P2.2Na/c1-6(22)18-10-13(26)11(24)7(4-21)35-16(10)36-39(31,32)37-38(29,30)33-5-8-12(25)14(27)15(34-8)20-3-2-9(23)19-17(20)28;;/h2-3,7-8,10-16,21,24-27H,4-5H2,1H3,(H,18,22)(H,29,30)(H,31,32)(H,19,23,28);;/q;2*+1/p-2/t7-,8-,10-,11+,12-,13-,14-,15?,16?;;/m1../s1

InChI key

HXWKMJZFIJNGES-QCVFHWOISA-L

General description

Uridine diphosphate (UDP)-GalNAc acts as a precursor in the biosynthesis of O-linked oligosaccharide. It also acts as a substrate for synthesis of chitin, a vital element of cell walls in fungi and of exoskeletons of arthropods and insects.

Application

Uridine 5′-diphospho-N-acetylgalactosamine disodium salt has been used as a substrate for polypeptide N-acetylgalactosaminyltransferase (ppGalNAc-T).

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This Item
U4375U4500U5625
biological source

synthetic (organic)

biological source

bakers yeast

biological source

bovine milk, rabbit muscle, yeast

biological source

Saccharomyces cerevisiae, enzyme from bovine liver (catalase), enzyme from rabbit muscle (LDH)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

assay

≥97%

assay

≥98%

assay

≥97.0%

assay

98-100%

form

powder

form

powder

form

powder

form

powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

solubility

water: 50 mg/mL, clear, colorless

solubility

water: 50 mg/mL, clear to hazy, colorless

solubility

water: 50 mg/mL, clear, colorless

solubility

water: 50 mg/mL, clear, colorless


Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Related Content

Glycobiology and Glycoproteomics Brochure


Expression of UDP-GalNAc: polypeptide N-acetylgalactosaminyltransferase isozymes T1 and T2 in human colorectal cancer
Kohsaki T, et al.
Journal of Gastroenterology, 35(11), 840-848 (2000)
Earnest James Paul Daniel et al.
Glycobiology, 30(11), 910-922 (2020-04-19)
A family of polypeptide GalNAc-transferases (GalNAc-Ts) initiates mucin-type O-glycosylation, transferring GalNAc onto hydroxyl groups of Ser and Thr residues of target substrates. The 20 GalNAc-T isoenzymes in humans are classified into nine subfamilies according to sequence similarity. GalNAc-Ts select their
Amanda Fritzen et al.
PLoS neglected tropical diseases, 12(7), e0006598-e0006598 (2018-07-10)
Crimean-Congo hemorrhagic fever virus (CCHFV) causes severe acute human disease with lethal outcome. The knowledge about the immune response for this human health threat is highly limited. In this study, we have screened the glycoprotein of CCHFV for novel linear



Global Trade Item Number

SKUGTIN
U5252-25MG04061833008195
U5252-100MG04061837409745
U5252-5MG04061837409752

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