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Urea

Name: Urea
Brand: SIGMA

meets USP testing specifications

Synonym(s):

Carbamide, Carbonyldiamide

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About This Item

Linear Formula:

NH₂CONH₂

CAS Number:

57-13-6

Molecular Weight:

60.06

UNSPSC Code:

12352111

NACRES:

NA.75

PubChem Substance ID:

24900650

EC Number:

200-315-5

Beilstein/REAXYS Number:

635724

MDL number:

MFCD00008022

Assay:

98.0-102.0%

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Properties

Quality Level

200

agency

USP/NF, meets USP testing specifications

assay

98.0-102.0%

form

solid

dilution

(for analytical testing)

mp

132-135 °C (lit.)

solubility

H₂O: soluble 480 g/L at 20 °C

density

1.335 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

SMILES string

NC(N)=O

InChI

1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)

InChI key

XSQUKJJJFZCRTK-UHFFFAOYSA-N

Gene Information

human ... CA1(759), CA2(760)
rat ... Ppm1a(24666)

Description

Application

Used for the denaturation of proteins and as a mild solubilization agent for insoluble or denatured proteins. Useful for renaturing proteins from samples already denatured with 6 M guanidine chloride such as inclusion bodies. May be used with guanidine hydrochloride and dithiothreitrol (DTT) in the refolding of denatured proteins into their native or active form.

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This Item	PHR1406	U0600000	BP350
Sigma-Aldrich U4884 Urea	Supelco PHR1406 Urea	U0600000 Urea	BP350 Urea
Quality Level 200	Quality Level 300	Quality Level -	Quality Level -
application(s) pharmaceutical (small molecule)	application(s) pharmaceutical (small molecule)	application(s) pharmaceutical (small molecule)	application(s) pharmaceutical pharmaceutical small molecule
assay 98.0-102.0%	assay -	assay -	assay -
solubility H₂O: soluble 480 g/L at 20 °C	solubility -	solubility -	solubility -
form solid	form -	form -	form solid
density 1.335 g/mL at 25 °C (lit.)	density 1.335 g/mL at 25 °C (lit.)	density 1.335 g/mL at 25 °C (lit.)	density 1.335 g/mL at 25 °C (lit.)

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Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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A unique role for p53 in the regulation of M2 macrophage polarization.

L Li et al.

Cell death and differentiation, 22(7), 1081-1093 (2014-12-20)

P53 is critically important in preventing oncogenesis but its role in inflammation in general and in the function of inflammatory macrophages in particular is not clear. Here, we show that bone marrow-derived macrophages exhibit endogenous p53 activity, which is increased

Diagnosis of tuberculous meningitis by detection of tuberculostearic acid in cerebrospinal fluid.

G L French et al.

Lancet (London, England), 2(8551), 117-119 (1987-07-18)

Tuberculostearic acid, a structural component of Mycobacterium tuberculosis, was identified by gas chromatography/mass spectrometry with selected ion monitoring in cerebrospinal fluid (CSF) from 13 patients with proven and 8 out of 9 patients with suspected tuberculous meningitis; the negative result

A mechanically and electrically self-healing supercapacitor.

Hua Wang et al.

Advanced materials (Deerfield Beach, Fla.), 26(22), 3638-3643 (2014-02-21)

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Global Trade Item Number

SKU	GTIN
U4884-100G	04061837409677
U4884-500G	04061837409684
U4884-5KG	04061837409691
U4884-1KG	04061826759318

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