Key Documents

View All Documentation

KGF human

Name: KGF human
Brand: SIGMA

Animal-component free, recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC), suitable for cell culture

Synonym(s):

Fibroblast Growth Factor-7, HBGF-7, Keratinocyte Growth Factor

Select a Size

Change View

Pack Size	SKU	Availability	Price

About This Item

NACRES:

NA.32

UNSPSC Code:

12352202

Pricing and availability is not currently available.

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

biological source

human

recombinant

expressed in E. coli

assay

≥95% (HPLC), ≥95% (SDS-PAGE)

form

lyophilized

potency

≤10 ng/mL ED₅₀

mol wt

18.9 kDa

packaging

pkg of 10 μg

technique(s)

cell culture | mammalian: suitable

impurities

<0.1 EU/μg endotoxin, tested

color

off-white to yellow

UniProt accession no.

P21781

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... FGF7(2252)

Description

General description

Fibroblast growth factor-7 (FGF-7) is a member of the fibroblast growth factor family. FGF family members possess broad mitogenic and cell survival activities. The gene encoding this protein is localized on human chromosome 15q21.1.

Biochem/physiol Actions

Fibroblast growth factor (FGF) family members are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF7 is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. This protein associates with and activates fibroblast growth factor receptors (FGFRs). Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, re-epithelialization of wounds, hair development and early lung organogenesis.

Physical form

Lyophilized from 15 mM Sodium Phosphate pH 7.0 + 0.25 M NaCl.

Preparation Note

Centrifuge the vial prior to opening. Reconstitute in 1x PBS to a concentration of 0.5-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a stabilizer (example 5% Trehalose) and store in working aliquots at -20°C to -80°C.

Other Notes

MCNDMTPEQM ATNVNCSSPE RHTRSYDYME GGDIRVRRLF CRTQWYLRID KRGKVKGTQE MKNNYNIMEI RTVAVGIVAI KGVESEFYLA MNKEGKLYAK KECNEDCNFK ELILENHYNT YASAKWTHNG GEMFVALNQK GIPVRGKKTK KEQKTAHFLP MAIT

Compare Similar Items

View Full Comparison

Show Differences

1 of 1

This Item	H6666	K1757	SRP3038
Sigma-Aldrich SRP3100 KGF human	Sigma-Aldrich H6666 Keratinocyte Growth Factor human	Sigma-Aldrich K1757 Keratinocyte Growth Factor human	Sigma-Aldrich SRP3038 FGF-16 human
biological source human	biological source human	biological source human	biological source human
assay ≥95% (HPLC), ≥95% (SDS-PAGE)	assay >95% (SDS-PAGE)	assay ≥95% (SDS-PAGE and HPLC)	assay ≥95% (HPLC), ≥95% (SDS-PAGE)
recombinant expressed in E. coli	recombinant expressed in HEK 293 cells	recombinant expressed in E. coli	recombinant expressed in E. coli
technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable
form lyophilized	form lyophilized powder	form powder	form lyophilized
shipped in wet ice	shipped in -	shipped in -	shipped in wet ice

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

A family-based association study after genome-wide linkage analysis identified two genetic loci for renal function in a Mongolian population.

Park H

Kidney International, 83(2), 285-292 (2013)

The Fibroblast Growth Factor signaling pathway.

Ornitz DM and Itoh N

Wiley Interdisciplinary Reviews. Systems Biology and Medicine, 4(3), 215-266 (2015)

Early microRNA expression profile as a prognostic biomarker for the development of pelvic inflammatory disease in a mouse model of chlamydial genital infection.

Laxmi Yeruva et al.

mBio, 5(3), e01241-e01214 (2014-06-26)

It is not currently possible to predict the probability of whether a woman with a chlamydial genital infection will develop pelvic inflammatory disease (PID). To determine if specific biomarkers may be associated with distinct chlamydial pathotypes, we utilized two Chlamydia

View All Related Papers

Global Trade Item Number

SKU	GTIN
SRP3100-10UG	04061837208003

Questions

Reviews

No rating value