For C-Phycocyanin from Spirulina sp. (P2172), the protein content, as determined by the Lowry method, is reported in the Certificate of Analysis and is typically in the range of 30–50%. However, this value reflects the total protein content in the lyophilized powder, not the purity of c-Phycocyanin itself. The product is only partially purified, and other proteins may be present. Purity is not determined by the Lowry method but rather by SDS-PAGE, which assesses the presence of major bands. Therefore, the protein content determined by the Lowry method should not be used as a direct measure of c-Phycocyanin purity.
P2172
C-Phycocyanin from Spirulina sp.
lyophilized powder
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About This Item
Form:
lyophilized powder
Biological source:
Spirulina
Pricing and availability is not currently available.
biological source
Spirulina
Quality Level
form
lyophilized powder
composition
Protein, ~40% Lowry
concentration
30-50% protein (Lowry)
storage temp.
2-8°C
Gene Information
Spirulina ... cpcA(41380954), cpcB(41380955)
General description
C-Phycocyanin is a protein pigment, that is soluble in water. It is an important constituent of Spirulina platensis.
Application
C-Phycocyanin from Spirulina sp. has been used:
- as a standard to characterize the fluorescence interactions and oxidation behaviors for model compounds
- as a standard to confirm the antibacterial activity
- to characterize the recombinantly expressed α-subunit of C-phycocyanin from Synechocystis sp. PCC6803 (HisCPC)
- to identify the phycocyanin from water extracted Spirulina maxima sample
Biochem/physiol Actions
C-phycocyanin can act as an active inhibitor of A53Tα-synuclein. It possess anti-inflammatory properties.
C-phycocyanin, a biliprotein with antioxidant properties, was shown to induce apoptosis in HeLa cells by stimulating expression of pro-apoptotic genes as well as by inducing increased release of cytochrome c from the mitochondria. [1]
Packaging
Package size based on protein content
Physical form
Partially purified, contains sucrose, dithioerythritol and sodium azide as preservatives
1 of 1
This Item | |||
|---|---|---|---|
| biological source Spirulina | biological source - | biological source - | biological source - |
| concentration 30-50% protein (Lowry) | concentration ≥10.0 mg/mL (UV) | concentration - | concentration 5 mg/mL in DMSO |
| form lyophilized powder | form - | form lyophilized powder | form DMSO solution |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. −20°C |
| Gene Information Spirulina ... cpcA(41380954), cpcB(41380955) | Gene Information - | Gene Information - | Gene Information - |
| Quality Level 200 | Quality Level 100 | Quality Level 200 | Quality Level 200 |
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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C-phycocyanin: a potent peroxyl radical scavenger in vivo and in vitro
Bhat VB and Madyastha KM
Biochemical and biophysical research communications, 275(1), 20-25 (2000)
Jun-Ichi Ishihara et al.
Biochemistry and biophysics reports, 34, 101469-101469 (2023-05-01)
The one-dimensional multicellular cyanobacterium, Anabaena sp. PCC 7120, exhibits a simple topology consisting of two types of cells under the nitrogen-depleted conditions. Although the differentiated (heterocyst) and undifferentiated cells (vegetative cells) were distinguished by their cellular shapes, we found that
C-Phycocyanin from Spirulina Inhibits ?-Synuclein and Amyloid ?-Fibril Formation but Not Amorphous Aggregation
Liu Y, et al.
Journal of Natural Products, 82(1), 66-73 (2019)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| P2172-10MG | 04061834362661 |
| P2172-25MG | 04061833273418 |
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The Protein Content (Lowry) can be used as purity of c-Phycocyanin?
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