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I9759

Ile-Pro-Ile

≥97% (HPLC), Dipeptidyl peptidase IV inhibitor, powder

Synonym(s):

Diprotin A

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About This Item

Empirical Formula (Hill Notation):
C17H31N3O4
CAS Number:
Molecular Weight:
341.45
UNSPSC Code:
51111800
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥97% (HPLC)
Form:
powder
Quality level:
Pricing and availability is not currently available.
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Product Name

Ile-Pro-Ile, ≥97% (HPLC)

Quality Level

assay

≥97% (HPLC)

form

powder

solubility

water: 1 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

CCC(C)C(N)C(=O)N1CCCC1C(=O)NC(C(C)CC)C(O)=O

InChI

1S/C17H31N3O4/c1-5-10(3)13(18)16(22)20-9-7-8-12(20)15(21)19-14(17(23)24)11(4)6-2/h10-14H,5-9,18H2,1-4H3,(H,19,21)(H,23,24)

InChI key

JNTMAZFVYNDPLB-UHFFFAOYSA-N

Application

Ile-Pro-Ile has been used as a supplement for blood collection for hormone measurement[1] and used in Islets cell culture to stabilize glucagon-like peptide-1 (GLP-1). It has also been used to inhibit the breakdown of gonadotropin-inhibitory hormone (GnIH) following serum collection.

Biochem/physiol Actions

Dipeptidyl peptidase IV Inhibitor. Inhibits entry of HIV-1 or HIV-2
Inhibitor of dipeptidyl peptidase IV. Inhibits entry of HIV-1 or HIV-2 into T lymphoblastoid and monocytoid cell lines.

Features and Benefits

This compound is featured on the Neuropeptidases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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This Item
416200C8273B5386
assay

≥97% (HPLC)

assay

≥95% (HPLC)

assay

≥98% (TLC and HPLC)

assay

≥97% (HPLC)

form

powder

form

amorphous solid

form

powder

form

powder

Quality Level

200

Quality Level

100

Quality Level

300

Quality Level

200

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

solubility

water: 1 mg/mL, clear, colorless

solubility

water: 1 mg/mL, DMSO: 5 mg/mL

solubility

DMSO: soluble, ethanol: soluble

solubility

aqueous base: soluble, clear


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Pádraigín A Harnedy et al.
Food research international (Ottawa, Ont.), 106, 598-606 (2018-03-28)
Large quantities of low-value protein rich co-products, such as salmon skin and trimmings, are generated annually. These co-products can be upgraded to high-value functional ingredients. The aim of this study was to assess the antidiabetic potential of salmon skin gelatin
Pancreatic alpha cell-derived glucagon-related peptides are required for beta cell adaptation and glucose homeostasis
Traub S, et al.
Cell Reports, 18(13), 3192-3203 (2017)
Brandon L Panaro et al.
Molecular metabolism, 19, 65-74 (2018-11-28)
Fibroblast Activation Protein (FAP), an enzyme structurally related to dipeptidyl peptidase-4 (DPP-4), has garnered interest as a potential metabolic drug target due to its ability to cleave and inactivate FGF-21 as well as other peptide substrates. Here we investigated the



Global Trade Item Number

SKUGTIN
I9759-25MG04061833865767
I9759-5MG04061833865774

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