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About This Item
Empirical Formula (Hill Notation):
C17H31N3O4
CAS Number:
Molecular Weight:
341.45
UNSPSC Code:
51111800
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Pricing and availability is not currently available.
Product Name
Ile-Pro-Ile, ≥97% (HPLC)
Quality Level
assay
≥97% (HPLC)
form
powder
solubility
water: 1 mg/mL, clear, colorless
storage temp.
−20°C
SMILES string
CCC(C)C(N)C(=O)N1CCCC1C(=O)NC(C(C)CC)C(O)=O
InChI
1S/C17H31N3O4/c1-5-10(3)13(18)16(22)20-9-7-8-12(20)15(21)19-14(17(23)24)11(4)6-2/h10-14H,5-9,18H2,1-4H3,(H,19,21)(H,23,24)
InChI key
JNTMAZFVYNDPLB-UHFFFAOYSA-N
Application
Ile-Pro-Ile has been used as a supplement for blood collection for hormone measurement[1] and used in Islets cell culture to stabilize glucagon-like peptide-1 (GLP-1). It has also been used to inhibit the breakdown of gonadotropin-inhibitory hormone (GnIH) following serum collection.
Biochem/physiol Actions
Dipeptidyl peptidase IV Inhibitor. Inhibits entry of HIV-1 or HIV-2
Inhibitor of dipeptidyl peptidase IV. Inhibits entry of HIV-1 or HIV-2 into T lymphoblastoid and monocytoid cell lines.
Features and Benefits
This compound is featured on the Neuropeptidases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
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This Item | |||
|---|---|---|---|
| assay ≥97% (HPLC) | assay ≥95% (HPLC) | assay ≥98% (TLC and HPLC) | assay ≥97% (HPLC) |
| form powder | form amorphous solid | form powder | form powder |
| Quality Level 200 | Quality Level 100 | Quality Level 300 | Quality Level 200 |
| storage temp. −20°C | storage temp. 2-8°C | storage temp. −20°C | storage temp. −20°C |
| solubility water: 1 mg/mL, clear, colorless | solubility water: 1 mg/mL, DMSO: 5 mg/mL | solubility DMSO: soluble, ethanol: soluble | solubility aqueous base: soluble, clear |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Pádraigín A Harnedy et al.
Food research international (Ottawa, Ont.), 106, 598-606 (2018-03-28)
Large quantities of low-value protein rich co-products, such as salmon skin and trimmings, are generated annually. These co-products can be upgraded to high-value functional ingredients. The aim of this study was to assess the antidiabetic potential of salmon skin gelatin
Pancreatic alpha cell-derived glucagon-related peptides are required for beta cell adaptation and glucose homeostasis
Traub S, et al.
Cell Reports, 18(13), 3192-3203 (2017)
Brandon L Panaro et al.
Molecular metabolism, 19, 65-74 (2018-11-28)
Fibroblast Activation Protein (FAP), an enzyme structurally related to dipeptidyl peptidase-4 (DPP-4), has garnered interest as a potential metabolic drug target due to its ability to cleave and inactivate FGF-21 as well as other peptide substrates. Here we investigated the
Global Trade Item Number
| SKU | GTIN |
|---|---|
| I9759-25MG | 04061833865767 |
| I9759-5MG | 04061833865774 |



