D3506

Sodium diethyldithiocarbamate trihydrate

≥97% (perchloric acid titration), chelating agent, powder or crystals

• Synonym(s): Cupral, Diethyldithiocarbamic acid sodium salt
• Linear Formula: (C₂H₅)₂NCSSNa · 3H₂O
• CAS Number: 20624-25-3
• Molecular Weight: 225.31
• UNSPSC Code: 12352200
• NACRES: NA.77
• PubChem Substance ID: 57654092
• EC Number: 205-710-6
• MDL number: MFCD00150617
• Beilstein/REAXYS Number: 3920507
• Assay: ≥97% (perchloric acid titration)
• Form: powder or crystals

Properties

• Product Name: Sodium diethyldithiocarbamate trihydrate,
• vapor density: 5.9 (vs air)
• Quality Segment: 200
• assay: ≥97% (perchloric acid titration)
• form: powder or crystals
• mp: 95-98.5 °C (lit.)
• solubility: water: 1 g/10 mL, slightly hazy
• storage temp.: room temp
• SMILES string: [H]O[H].[H]O[H].[H]O[H].CCN(CC)C(=S)S[Na]
• InChI: 1S/C5H11NS2.Na.3H2O/c1-3-6(4-2)5(7)8;;;;/h3-4H2,1-2H3,(H,7,8);;3*1H2/q;+1;;;/p-1
• InChI key: WWGXHTXOZKVJDN-UHFFFAOYSA-M

Description

Application

Spin trap used in conjunction with Fe²⁺ to detect NO in brain, kidney, liver, and other tissues.

Spin trap used in conjunction with Fe²⁺ to detect NO in brain, kidney, liver, and other tissues. Simultaneous direct measurement of NO* and pO₂ has been reported. A copper chelator, it has been used to quantitate copper in biological materials by ESR and is an inhibitor of superoxide dismutase, ascorbate oxidase, and other enzymes.

Biochem/physiol Actions

Inhibits induction of macrophage nitric oxide synthase.

Features and Benefits

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Dopamine, Norepinephrine and Epinephrine Synthesis page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Disclaimer

May form insoluble oxidation products in storage. Sensitivity in colorimetric copper determination not usually affected.

Safety Information

• pictograms: GHS05,GHS07
• signalword: Danger
• hcodes: H302,H315,H318
• pcodes: P264 - P270 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves