90101

Ampliflu^™ Red

suitable for fluorescence, ≥98.0% (HPLC)

• Synonym(s): 10-Acetyl-3,7-dihydroxyphenoxazine
• Empirical Formula (Hill Notation): C₁₄H₁₁NO₄
• CAS Number: 119171-73-2
• Molecular Weight: 257.24
• NACRES: NA.32
• PubChem Substance ID: 329769846
• UNSPSC Code: 12352108
• MDL number: MFCD00467861

Properties

• Quality Segment: 100
• assay: ≥98.0% (HPLC)
• form: powder
• mol wt: 257.24 g/mol
• concentration: 90-100 % (w/w) (Ampliflu Red)
• color: slightly brown-red, white to slightly brown
• solubility: water: slightly soluble at 20 °C
• fluorescence: λ_ex 571 nm; λ_em 585 nm in DMSO
• suitability: suitable for fluorescence
• storage temp.: 2-8°C
• SMILES string: CC(=O)N1c2ccc(O)cc2Oc3cc(O)ccc13
• InChI: 1S/C14H11NO4/c1-8(16)15-11-4-2-9(17)6-13(11)19-14-7-10(18)3-5-12(14)15/h2-7,17-18H,1H3
• InChI key: PKYCWFICOKSIHZ-UHFFFAOYSA-N

Description

Application

Ampliflu^™ Red has been used to study mitochondrial abnormalities and oxidative stress related to Parkinson’s Disease.[1] Ampliflu^™ Red assay was suitable as an alternative indicator assay for detecting the inhibition of hTPO (human thyroid peroxidase) activity.[2] Phospholipase D, an essential cellular process ingredient, used Ampliflu^™ Red (10-Acetyl-3,7-dihydroxyphenoxazine) to determine its activity.[3]Ampliflu^™ Red is used for the following applications:

• Quantification of inflammatory mediators[4]
• Determination of free and esterified cholesterol contents[5]
• Evaluation of compounds as substrates for GABA-AT compounds[6]

Legal Information

Ampliflu is a trademark of Sigma-Aldrich Co. LLC

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves