If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
72340
Nicotinamide
≥99.5% (HPLC)
Synonym(s):
Niacinamide, Nicotinic acid amide, Pyridine-3-carboxylic acid amide, Vitamin B3, Vitamin PP
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About This Item
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biological source
synthetic
Quality Level
assay
≥99.5% (HPLC)
form
powder or crystals
ign. residue
≤0.2%
loss
≤0.2% loss on drying, 20 °C (HV)
color
colorless to white
mp
128-131 °C
anion traces
chloride (Cl-): ≤50 mg/kg, sulfate (SO42-): ≤150 mg/kg
cation traces
Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Na: ≤50 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg
application(s)
cell analysis
SMILES string
NC(=O)c1cccnc1
InChI
1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)
InChI key
DFPAKSUCGFBDDF-UHFFFAOYSA-N
Gene Information
human ... PARP1(142), SIRT2(22933)
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Related Categories
1 of 4
This Item | |||
|---|---|---|---|
| biological source synthetic | biological source synthetic (organic) | biological source synthetic | biological source - |
| assay ≥99.5% (HPLC) | assay ≥98% (HPLC) | assay ≥98.5% (HPLC) | assay - |
| form powder or crystals | form powder | form powder | form solid |
| application(s) cell analysis | application(s) - | application(s) - | application(s) liquid formulation |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 500 |
| mp 128-131 °C (lit.) | mp 128-131 °C (lit.) | mp 128-131 °C (lit.) | mp 128-131 °C (sublimed) |
General description
Application
- to study its effect on the expression of sirtuin 1
- in nicotinamide adenine dinucleotide/nicotinamide adenine dinucleotide phopshate (NAD+/NADH) cycling assay
- in cell lysis buffer, to serve as a sirtuin 1 inhibitor in order to study its role in resveratrol (RSV)-stimulated hepatitis B virus replication[1]
Biochem/physiol Actions
Other Notes
related product
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
302.0 °F - closed cup
flash_point_c
150 °C - closed cup
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| 72340-100G | 04061832861159 |
| 72340-1KG | 04061826715284 |
| 72340-250G | 04061832861166 |
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How can I determine the shelf life / expiration / retest date of this product?
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what is the storage temperature 7234 nicotinamide
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In powder form, this material may be stored at room temperature. While the solution stability has not been evaluated, stock solutions are expected to be stable at low pH levels when refrigerated at 2 - 8°C. The product is known to degrade gradually, for optimum quality prepare fresh.
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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