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112003

Hippuric acid

98%

Synonym(s):

N-Benzoylglycine, Benzoylaminoacetic acid

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About This Item

Linear Formula:
C6H5CONHCH2COOH
CAS Number:
Molecular Weight:
179.17
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
207-806-3
MDL number:
Beilstein/REAXYS Number:
1073987
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Product Name

Hippuric acid, 98%

Quality Level

assay

98%

form

powder, crystals or chunks

mp

187-191 °C (lit.)

application(s)

peptide synthesis

SMILES string

OC(=O)CNC(=O)c1ccccc1

InChI

1S/C9H9NO3/c11-8(12)6-10-9(13)7-4-2-1-3-5-7/h1-5H,6H2,(H,10,13)(H,11,12)

InChI key

QIAFMBKCNZACKA-UHFFFAOYSA-N

Gene Information

rat ... Akr1b1(24192)

Application

Hippuric acid can be used to study cell biology, chemical biology, bioactive small molecules, amino acid derivatives, peptide synthesis, chemical synthesis and nutrition. Hippuric acid has been used to inform the metabolism and urinary excretion of procyanidins.

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This Item
8.20649H9380381071
form

powder, crystals or chunks

form

solid

form

powder

form

powder, crystals or chunks

assay

98%

assay

≥97.5% (acidimetric)

assay

≥99%

assay

99%

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

mp

187-191 °C (lit.)

mp

188-190 °C

mp

-

mp

324 °C (dec.) (lit.)

application(s)

peptide synthesis

application(s)

-

application(s)

detection

application(s)

peptide synthesis

Gene Information

rat ... Akr1b1(24192)

Gene Information

-

Gene Information

-

Gene Information

-


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Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2



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H Ukai et al.
Occupational and environmental medicine, 51(8), 523-529 (1994-08-01)
Exposure monitoring by personal diffusive samplers, biological monitoring of toluene exposure by urinary hippuric acid determination, haematology, serum biochemistry for liver function, and a subjective symptom survey by questionnaire were conducted on 303 male solvent workers. They were exposed to
Justin J J van der Hooft et al.
Analytical chemistry, 84(16), 7263-7271 (2012-07-26)
In dietary polyphenol exposure studies, annotation and identification of urinary metabolites present at low (micromolar) concentrations are major obstacles. To determine the biological activity of specific components, it is necessary to have the correct structures and the quantification of the
T Takada et al.
Scientific reports, 8(1), 11147-11147 (2018-07-26)
Chronic kidney disease (CKD) patients accumulate uremic toxins in the body, potentially require dialysis, and can eventually develop cardiovascular disease. CKD incidence has increased worldwide, and preventing CKD progression is one of the most important goals in clinical treatment. In



Global Trade Item Number

SKUGTIN
112003-100G04061838699404
112003-500G04061838699411
112003-5G04061838699428

Questions

1–3 of 3 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. Can this chemical be used in vitro? If so, how to dilute it?

    1 answer
    1. This product has not been tested for in vivo or in vitro applications. Suitability for in vitro use will need to be validated by the end user. Hippuric acid is soluble in water at 3 - 4 mg/mL. Sodium or ammonium hydroxide is suggested for higher concentrations. It may be helpful to view peer-reviewed articles. Please see the publications in the link below:

      https://www.sigmaaldrich.com/search/112003?focus=papers&page=1&perpage=30&sort=relevance&term=112003&type=citation_search

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