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Ethyl parahydroxybenzoate

Name: Ethyl parahydroxybenzoate
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Ethyl 4-hydroxybenzoate, Ethylparaben

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About This Item

Linear Formula:

HOC₆H₄CO₂C₂H₅

CAS Number:

120-47-8

Molecular Weight:

166.17

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329799028

MDL number:

MFCD00002353

Beilstein/REAXYS Number:

1101972

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Properties

grade

pharmaceutical primary standard

API family

parabens

manufacturer/tradename

EDQM

bp

297-298 °C (lit.)

mp

114-117 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

CCOC(=O)c1ccc(O)cc1

InChI

1S/C9H10O3/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6,10H,2H2,1H3

InChI key

NUVBSKCKDOMJSU-UHFFFAOYSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Ethyl parahydroxybenzoate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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1 of 1

This Item	1267000	PHR1011	79577
E2425000 Ethyl parahydroxybenzoate	USP 1267000 Ethylparaben	Supelco PHR1011 Ethylparaben	Supelco 79577 Ethylparaben
grade pharmaceutical primary standard	grade pharmaceutical primary standard	grade certified reference material, pharmaceutical secondary standard	grade certified reference material, TraceCERT^®
manufacturer/tradename EDQM	manufacturer/tradename USP	manufacturer/tradename -	manufacturer/tradename Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
application(s) pharmaceutical (small molecule)	application(s) pharmaceutical (small molecule)	application(s) cleaning products cosmetics flavors and fragrances food and beverages personal care pharmaceutical (small molecule)	application(s) -
format neat	format neat	format neat	format neat
API family parabens	API family parabens	API family parabens	API family -
bp 297-298 °C (lit.)	bp 297-298 °C (lit.)	bp 297-298 °C (lit.)	bp 297-298 °C (lit.)

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Simultaneous analysis of antioxidants and preservatives in cosmetics by supercritical fluid extraction combined with liquid chromatography-mass spectrometry.

Maw-Rong Lee et al.

Journal of chromatography. A, 1120(1-2), 244-251 (2006-03-04)

This study evaluated supercritical fluid extraction (SFE) combined with liquid chromatography-mass spectrometry (LC-MS) to determine trace preservatives and antioxidants including methylparaben (MP), ethylparaben (EP), propylparaben (PP), butylparaben (BP), butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT), alpha-tocopherol (alpha-t) and alpha-tocopherol acetate (alpha-ta)

Molecular dissection of the role of two methyltransferases in the biosynthesis of phenolglycolipids and phthiocerol dimycoserosate in the Mycobacterium tuberculosis complex.

Esther Pérez et al.

The Journal of biological chemistry, 279(41), 42584-42592 (2004-08-05)

A few mycobacterial species, most of which are pathogenic for humans, produce dimycocerosates of phthiocerol (DIM) and of glycosylated phenolphthiocerol, also called phenolglycolipid (PGL), two groups of molecules shown to be important virulence factors. The biosynthesis of these molecules is

Metabolism of parabens (4-hydroxybenzoic acid esters) by hepatic esterases and UDP-glucuronosyltransferases in man.

Suzanne Abbas et al.

Drug metabolism and pharmacokinetics, 25(6), 568-577 (2010-10-12)

Parabens (alkyl esters of 4-hydroxybenzoic acid) are widely used as preservatives in drugs, cosmetic products, and foodstuffs. Safety concerns have recently increased due to the potential health risks associated to exposure to large amounts of these substances. Biotransformation of parabens

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Global Trade Item Number

SKU	GTIN
E2425000	04061833793398

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