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C4255

Creatinine

anhydrous, ≥98%

Synonym(s):

2-Amino-1-methyl-2-imidazolin-4-one, 2-Imino-1-methylimidazolidin-4-one, 2-Imino-N-methylhydantoin

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About This Item

Empirical Formula (Hill Notation):
C4H7N3O
CAS Number:
60-27-5
Molecular Weight:
113.12
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
24892677
EC Number:
200-466-7
Beilstein/REAXYS Number:
112061
MDL number:
MFCD00059730
Assay:
≥98%
Form:
powder
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grade

anhydrous

Quality Level

200

assay

≥98%

form

powder

mp

295 °C (dec.) (lit.)

SMILES string

CN1CC(=O)N=C1N

InChI

1S/C4H7N3O/c1-7-2-3(8)6-4(7)5/h2H2,1H3,(H2,5,6,8)

InChI key

DDRJAANPRJIHGJ-UHFFFAOYSA-N

General description

Creatinine is a breakdown product formed by the degradation of creatine phosphate from muscles. The kidneys extract creatinine from the body by filtering almost all of it from the blood and excreting it in the urine.[1] Serum creatinine is the most commonly used indicator for renal functioning. In chemical synthesis, creatinine is used as a heterocyclic nitrogenous compound that produces electron-rich and highly basic creatinine derivatives.

Application

Creatinine can be used as:
  • A nitrogen donor building block to prepare nitrogen-containing heterocyclic derivatives.
  • A reactant to synthesize donor-acceptor type carbon nitride copolymer, which is used as a photocatalyst in hydrogen production.
  • A starting material to prepare creatol(2-amino-1,5-dihydro-5-hydroxy methylimidazol-4-one) via creatinine chloramine.
  • A reactant to synthesize 3-substituted-3-hydroxyisatins by gold-catalyzed aldolization with various isatins.

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This Item
PHR1462NIST914B1150353
Creatinine anhydrous, ≥98%

Sigma-Aldrich

C4255

Creatinine

Creatinine Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1462

Creatinine

Creatinine NIST® SRM® 914b

NIST914B

Creatinine

Creatinine United States Pharmacopeia (USP) Reference Standard

USP

1150353

Creatinine

assay

≥98%

assay

-

assay

-

assay

-

Quality Level

200

Quality Level

300

Quality Level

-

Quality Level

-

mp

295 °C (dec.) (lit.)

mp

295 °C (dec.) (lit.)

mp

295 °C (dec.) (lit.)

mp

295 °C (dec.) (lit.)

form

powder

form

-

form

-

form

-

grade

anhydrous

grade

certified reference material, pharmaceutical secondary standard

grade

certified reference material

grade

pharmaceutical primary standard

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

554.0 °F - closed cup

flash_point_c

290 °C - closed cup

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000559476
0000531031
0000535134
0000535133
0000535135

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A Simple Conversion of Creatinine to Creatol via Creatinine Chloroamine
Ienaga K, et al.
Australian Journal of Chemistry, 68(2), 248-253 (2015)
Constructing creatinine-derived moiety as donor block for carbon nitride photocatalyst with extended absorption and spatial charge separation
Zong X, et al.
Applied Catalysis. B, Environmental, 291 (2021)
A review on creatinine measurement techniques
Mohabbati-Kalejahi E, et al.
Talanta, 97, 1-8 (2012)
View All Related Papers

Global Trade Item Number

SKUGTIN
C4255-10MG04061833491874
C4255-25G04061835556007
C4255-10G04061835555987
C4255-100G04061835555970
C4255-1KG04061835555994

Questions

1–3 of 3 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How to dissolve creatinine C4255?

    1 answer

    1. This product can be dissolved in water at 50 mg/mL. Please see the sample Certificate of Analysis for solubility information:

      https://www.sigmaaldrich.com/certificates/sapfs/PROD/sap/certificate_pdfs/COFA/Q14/C4255-25G0000256899.pdf

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  3. How is shipping temperature determined? And how is it related to the product storage temperature?

    0 answers

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