90527

Hydroxychloroquine sulfate

analytical standard

• Synonym(s): 7-Chloro-4-[4-(N-ethyl-N-b-hydroxyethylamino)-1-methylbutylamino]quinoline sulfate
• Empirical Formula (Hill Notation): C₁₈H₂₆ClN₃O · H₂SO₄
• CAS Number: 747-36-4
• Molecular Weight: 433.95
• NACRES: NA.24
• PubChem Substance ID: 329769919
• UNSPSC Code: 41116107
• EC Number: 212-019-3
• MDL number: MFCD00078203

Properties

• grade: analytical standard
• Quality Segment: 100
• assay: ≥95.0% (HPLC)
• shelf life: limited shelf life, expiry date on the label
• packaging: pkg of 50 mg
• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• impurities: ≤1.0% water
• color: white to off-white
• application(s): forensics and toxicology; pharmaceutical (small molecule); veterinary
• format: neat
• storage temp.: 2-8°C
• SMILES string: OS(O)(=O)=O.CCN(CCO)CCCC(C)Nc1ccnc2cc(Cl)ccc12
• InChI: 1S/C18H26ClN3O.H2O4S/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18;1-5(2,3)4/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21);(H2,1,2,3,4)
• InChI key: JCBIVZZPXRZKTI-UHFFFAOYSA-N
• Gene Information: human ... TLR7(51284), TLR9(54106)

Description

General description

Hydroxychloroquine Sulfate (Hydroxychloroquine Sulphate) is a salt of hydroxychloroquine (HCQ, Plaquenil), a 4-aminoquinoline based antiviral drug.

Application

Hydroxychloroquine Sulfate can be used as an analytical standard for the determination of the analyte in pharmaceutical formulations, and biological samples by various analytical techniques.

Biochem/physiol Actions

Hydroxychloroquine sulfate is an anti-inflammatory (via TNF), disease-modifying antirheumatic drug (DMARD), and a heme polymerase inhibitor.

Hydroxychloroquine sulfate is an anti-inflammatory (via TNF), disease-modifying antirheumatic drug (DMARD), and a heme polymerase inhibitor. It is used in treating malaria.

Safety Information

• pictograms: GHS07
• signalword: Warning
• pcodes: P264 - P270 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• hcodes: H302,H315,H319