44924

L-α-Phosphatidylcholine

suitable for microbiology, Surfactant and constituent of the liposomal carrier system

• Synonym(s): 1,2-Diacyl-sn-glycero-3-phosphocholine, L-α-Lecithin, Azolectin, PC, Lecithin from soybean, Soy lecithin, 1,2-Diacyl-sn-glycero-3-phosphocholine, 3-sn-Phosphatidylcholine, L-α-Lecithin, Azolectin, PC
• CAS Number: 8002-43-5
• MDL number: MFCD00082428
• UNSPSC Code: 41106212
• EC Number: 232-307-2
• NACRES: NA.85
• Beilstein/REAXYS Number: 5209585

Properties

• biological source: soybean
• Quality Segment: 200
• assay: ≥95% (phosphatides (as acetone insolubles))
• form: powder
• mol wt: observed mol wt 790.15 g/mol
• concentration: ≥25% (phosphatidylcholine, TLC)
• acid value: ≤35 mg KOH/g
• peroxide value: ≤5 meq/kg
• application(s): microbiology
• SMILES string: [P](=O)([O-])(OC[C@H](OC(=O)CCCCCCC\C=C/C\C=C/CCCCC)COC(=O)CCCCCCCCCCCCCCC)OCC[N+](C)(C)C
• InChI: 1S/C42H80NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h14,16,20-21,40H,6-13,15,17-19,22-39H2,1-5H3/b16-14-,21-20-/t40-/m1/s1
• InChI key: JLPULHDHAOZNQI-ZTIMHPMXSA-N

Description

General description

This L-α-phosphatidylcholine is extracted and purified from soybeans. It serves as a substrate for specific phospholipase present in all Listeria monocytogenes and some strains of Listeria ivanovii. If L-α-phosphatidylcholine is used in a solid medium the presence of organisms possessing the specific phospholipase can be detected. The phosphatidylcholine is cleaved which results in a precipitate which can be seen as opaque halo around the colonies.

Application

L-α-Phosphatidylcholine is one of several phospholipids used in membrane research and is often used as a component in liposomal drug delivery systems.
In this case it is added to culture media to differentiate the specific phospholipase producing microorganisms from those that cannot.

Biochem/physiol Actions

A major structural phospholipid in brain, comprising approx. 15% of total lipid; primarily localized to gray matter.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable