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43866

Salidroside

analytical standard

Synonym(s):

2-(4-Hydroxyphenyl)ethyl β−D-glucopyranoside, p-Hydroxyphenethyl glucopyranoside, Rhodioloside, Rhodosin, Tyrosol a-(β-D-glucopyranoside)

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About This Item

Empirical Formula (Hill Notation):
C14H20O7
CAS Number:
10338-51-9
Molecular Weight:
300.30
NACRES:
NA.24
PubChem Substance ID:
329756416
UNSPSC Code:
85151701
MDL number:
MFCD00210553
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grade

analytical standard

Quality Level

100

assay

≥98.0% (HPLC)

optical activity

[α]/D -29±2°, c = 0.5 in methanol

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

SMILES string

OC[C@H]1O[C@@H](OCCc2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C14H20O7/c15-7-10-11(17)12(18)13(19)14(21-10)20-6-5-8-1-3-9(16)4-2-8/h1-4,10-19H,5-7H2/t10-,11-,12+,13-,14-/m1/s1

InChI key

ILRCGYURZSFMEG-RKQHYHRCSA-N

General description

Salidroside is one of the major phenolic glycoside extracted from Rhodiola rosea L([1], which can show a broad-spectrum of pharmacological properties like anti-aging, anti-oxidant, anti-cancer and anti-inflammation.[2][1][3]

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Salidroside, the 8-O-β-D-glucoside of tyrosol, is the main bioactive component of Rhodiola species and is found mainly in the plant roots. It is biosynthesised in the tyrosine metabolism, with glucosylation of tyrosol being the final step[4]. It has been reported to be neuroprotective[2] [5][3] and one of the compounds responsible for the antidepressant and anxiolytic actions of Rhodiola rosea[6].

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

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This Item
PHR37821609534SMB00072
Salidroside analytical standard

Supelco

43866

Salidroside

Salidroside certified reference material, pharmaceutical secondary standard

Supelco

PHR3782

Salidroside

Salidroside United States Pharmacopeia (USP) Reference Standard

USP

1609534

Salidroside

Salidroside ≥95% (LC/MS-ELSD)

Sigma-Aldrich

SMB00072

Salidroside

grade

analytical standard

grade

certified reference material, pharmaceutical secondary standard

grade

pharmaceutical primary standard

grade

-

format

neat

format

-

format

neat

format

-

optical activity

[α]/D -29±2°, c = 0.5 in methanol

optical activity

-

optical activity

-

optical activity

-

Quality Level

100

Quality Level

300

Quality Level

-

Quality Level

-

application(s)

food and beverages

application(s)

pharmaceutical

application(s)

pharmaceutical (small molecule)

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

assay

≥98.0% (HPLC)

assay

-

assay

-

assay

≥95% (LC/MS-ELSD)

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Hazard Classifications

Eye Irrit. 2

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H319

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN2554
BCCM4309
BCCL2086
BCCH2071
BCCD9981

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Ze-qiang Qu et al.
PloS one, 7(1), e29641-e29641 (2012-01-12)
Previously we have demonstrated that a Rhodiola crenulata extract (RCE), containing a potent antioxidant salidroside, promotes neurogenesis in the hippocampus of depressive rats. The current study was designed to further investigate the protective effect of the RCE on neurogenesis in
Wieland Peschel et al.
Phytochemistry, 86, 92-102 (2012-11-10)
The demand for plant material of Rhodiola rosea L. (Crassulaceae) for medicinal use has increased recently, amid concerns about its quality and sustainability. We have analysed the content of phenylpropanoids (total rosavins) and salidroside in liquid extracts from 3-year old
A Panossian et al.
Phytotherapy research : PTR, 19(10), 819-838 (2005-11-02)
Plant adaptogens are compounds that increase the ability of an organism to adapt to environmental factors and to avoid damage from such factors. The beneficial effects of multi-dose administration of adaptogens are mainly associated with the hypothalamic-pituitary-adrenal (HPA) axis, a
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Global Trade Item Number

SKUGTIN
843914025004027269218669
843914100004027269218676
672068-1KG04061837660047
396311-25G04061833398456
396311-5G04061831983326
672068-250G04061833549568
672068-2.5KG04061837660054
43866-25MG04061833379622

Questions

1–2 of 2 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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