Key Documents

Albendazole sulfoxide

Name: Albendazole sulfoxide
Brand: SIAL

VETRANAL^®, analytical standard

Synonym(s):

Ricobendazole, Albendazole oxide, Albendazole sulfoxide, Methyl [5-(propane-1-sulfinyl)-1H-benzoimidazol-2-yl]-carbamate

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About This Item

Empirical Formula (Hill Notation):

C₁₂H₁₅N₃O₃S

CAS Number:

54029-12-8

Molecular Weight:

281.33

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329755155

MDL number:

MFCD00797922

Beilstein/REAXYS Number:

677664

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Properties

grade

analytical standard

Quality Level

100

product line

VETRANAL^®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

CCCS(=O)c1ccc2[nH]c(NC(=O)OC)nc2c1

InChI

1S/C12H15N3O3S/c1-3-6-19(17)8-4-5-9-10(7-8)14-11(13-9)15-12(16)18-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)

InChI key

VXTGHWHFYNYFFV-UHFFFAOYSA-N

Description

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Ricobendazole is a key metabolite of albendazole and acts as an anthelmintic. It has been shown to induce apoptosis in human cancer cell line HT-29, possibly by arresting cell cycle at the G₂/M phase.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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1 of 1

This Item	SMB00974	35394	32438
Supelco 35395 Albendazole sulfoxide	Sigma-Aldrich SMB00974 Albendazole sulfone	Supelco 35394 Albendazole sulfone	Supelco 32438 Parbendazole
grade analytical standard	grade -	grade analytical standard	grade analytical standard
format neat	format -	format neat	format neat
shelf life limited shelf life, expiry date on the label	shelf life -	shelf life limited shelf life, expiry date on the label	shelf life limited shelf life, expiry date on the label
technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) -	technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) HPLC: suitable, gas chromatography (GC): suitable
Quality Level 100	Quality Level 200	Quality Level 100	Quality Level 100
product line VETRANAL^®	product line -	product line VETRANAL^®	product line VETRANAL^®

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Explore all of our products under Albendazole sulfoxide

pictograms

GHS08,GHS07,GHS09

signalword

Warning

hcodes

H317,H361d,H373,H410

pcodes

P201 - P202 - P273 - P280 - P302 + P352 - P308 + P313

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - Skin Sens. 1 - STOT RE 2 Oral

target_organs

Adrenal gland,spleen,male reproductive organs,Blood

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

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Anti-echinococcal effect of verapamil involving the regulation of the calcium/calmodulin-dependent protein kinase II response in vitro and in a murine infection model.

Hai-Jun Gao et al.

Parasites & vectors, 14(1), 108-108 (2021-02-17)

Echinococcosis, which is caused by the larvae of cestodes of the genus Echinococcus, is a parasitic zoonosis that poses a serious threat to the health of humans and animals globally. Albendazole is the drug of choice for the treatment of

Application of ultra-performance columns in high-performance liquid chromatography for determination of albendazole and its metabolites in turkeys.

Tomasz Grabowski et al.

Biomedical chromatography : BMC, 25(10), 1159-1167 (2011-02-05)

Methods for determination of albendazole (ALB), albendazole sulfoxide (SOX) and albendazole sulfone (SON) in turkey blood plasma, using high-performance liquid chromatography (HPLC) with fluorescence detection, were developed. Moreover, comparison of HPLC columns with ultra-performance liquid chromatography (UPLC) columns was performed.

Pharmacokinetics and tissue residues of hydrochloric acid albendazole sulfoxide and its metabolites in crucian carp (Carassius auratus) after oral administration.

Zaijian Li et al.

Environmental toxicology and pharmacology, 33(2), 197-204 (2012-01-10)

The pharmacokinetics and residues elimination of hydrochloric acid albendazole sulfoxide (ABZSO) and its metabolites were studied in healthy crucian carp (Carassius auratus, 250 ± 30 g) kept at water temperatures of 10 °C and 25 °C. The concentrations of ABZSO

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Global Trade Item Number

SKU	GTIN
35395-10MG	04061835560417

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