No, this product is not USP grade and is intended for research use only. Please see the link below to review product 1808, Methylene Blue Solution, 1.4%, for in vitro diagnostic use.
https://www.sigmaaldrich.com/product/sial/1808
319112
Methylene Blue solution
0.05 wt. % in H2O
Synonym(s):
Ehrlich’s reagent III, Loeffler’s Methylene Blue
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About This Item
Empirical Formula (Hill Notation):
C16H18ClN3S
CAS Number:
Molecular Weight:
319.85
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
Colour Index Number:
52015
MDL number:
Beilstein/REAXYS Number:
3641570
Pricing and availability is not currently available.
form
liquid
Quality Level
concentration
0.05 wt. % in H2O
density
0.98 g/mL at 25 °C
λmax
665 nm
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
SMILES string
[Cl-].CN(C)c1ccc2N=C3C=C\C(C=C3Sc2c1)=[N+](/C)C
InChI
1S/C16H18N3S.ClH/c1-18(2)11-5-7-13-15(9-11)20-16-10-12(19(3)4)6-8-14(16)17-13;/h5-10H,1-4H3;1H/q+1;/p-1
InChI key
CXKWCBBOMKCUKX-UHFFFAOYSA-M
Application
Methylene Blue solution has been used to study structural alterations and p53 immune-expression in rats.
Biochem/physiol Actions
Methylene blue (MB) is a highly recognized histological dye. It plays a vital role in microbiology and pharmacology. It has been employed in staining living organisms and in methemoglobinemia treatment. MB exhibits maximum absorption at 664nm. Exposure to methylene blue leads to various health hazards such as increased heart rate, vomiting, shock, Heinz body formation, cyanosis, jaundice, quadriplegia and tissue necrosis in humans
1 of 1
This Item | |||
|---|---|---|---|
| concentration 0.05 wt. % in H2O | concentration 1.5% (1.5 g/ 100 mL) | concentration - | concentration 1.4 % (w/v) in 95% ethanol |
| form liquid | form liquid | form solution | form solution |
| application(s) diagnostic assay manufacturing | application(s) diagnostic assay manufacturing | application(s) - | application(s) - |
| storage temp. room temp | storage temp. room temp | storage temp. - | storage temp. 15-25°C |
| Quality Level 200 | Quality Level 100 | Quality Level - | Quality Level 500 |
| density 0.98 g/mL at 25 °C | density 1.0 g/mL at 20 °C | density - | density - |
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Storage Class
12 - Non Combustible Liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
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Methylene blue in photodynamic therapy: From basic mechanisms to clinical applications.
Tardivo JP
Photodiagnosis and Photodynamic Therapy, 2, 175-191 (2005)
Alexandru Grigoroiu et al.
Scientific reports, 10(1), 3947-3947 (2020-03-05)
Hyperspectral imaging (HSI) is being explored in endoscopy as a tool to extract biochemical information that may improve contrast for early cancer detection in the gastrointestinal tract. Motion artefacts during medical endoscopy have traditionally limited HSI application, however, recent developments
Microscopic structural alterations
and p53 immune-expression in adult
rat testis in response to intra-tunical versus
intra-parenchymal injection of methylene blue
and p53 immune-expression in adult
rat testis in response to intra-tunical versus
intra-parenchymal injection of methylene blue
Mazroa S A
International Journal of Clinical and Experimental Pathology, 9, 5346-5356 (2016)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 319112-100ML | 04061826694671 |
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