8.17034

Sodium dodecyl sulfate

EMPROVE^® ESSENTIAL, Ph. Eur.

• Synonym(s): Sodium dodecyl sulfate, Lauryl sulfate sodium salt, SDS, Dodecyl sodium sulfate, Dodecyl sodium sulfate, Dodecyl sulfate sodium salt, Lauryl sulfate sodium salt, SDS, Sodium lauryl sulfate
• Linear Formula: CH₃(CH₂)₁₁OSO₃Na
• CAS Number: 151-21-3
• Molecular Weight: 288.38
• EC Index Number: 205-788-1
• UNSPSC Code: 12352107
• Beilstein/REAXYS Number: 3599286
• MDL number: MFCD00036175

Properties

• agency: Ph. Eur.
• Quality Segment: 500
• product line: EMPROVE^® ESSENTIAL
• form: solid
• technique(s): API processing | nano-milling: suitable
• pH: 6-9 (20 °C, 10 g/L in H₂O)
• mp: 204-207 °C (lit.)
• transition temp: flash point >150 °C
• solubility: >130 g/L
• density: 1.1 g/cm³ at 20 °C
• application(s): liquid formulation; pharmaceutical; semi-solid formulation
• storage temp.: 15-25°C
• SMILES string: [Na+].CCCCCCCCCCCCOS([O-])(=O)=O
• InChI: 1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1
• InChI key: DBMJMQXJHONAFJ-UHFFFAOYSA-M

Description

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Anionic detergent

Sodium dodecyl sulfate is an anionic surfactant used in a wide variety of pharmaceutical and cosmetic formulations, mainly as surfactant or emulsifying agent in semi-solid formulations.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS02,GHS05,GHS07
• signalword: Danger
• hcodes: H228,H302 + H332,H315,H318,H335,H412
• pcodes: P210 - P273 - P280 - P301 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Flam. Sol. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 4.1B - Flammable solid hazardous materials
• wgk: WGK 2
• flash_point_f: 338.0 °F
• flash_point_c: 170 °C