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A-096

Aldosterone solution

100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

Synonym(s):

Aldosterone, 11β,21-Dihydroxy-3,20-dioxo-4-pregnen-18-al, 11β,21-Dihydroxypregn-4-ene-3,18,20-trione, 18-Aldocorticosterone, Reichstein X

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About This Item

Empirical Formula (Hill Notation):
C21H28O5
CAS Number:
52-39-1
Molecular Weight:
360.44
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329770641
EC Number:
200-835-2
Beilstein/REAXYS Number:
3224996
MDL number:
MFCD00051136
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grade

certified reference material

Quality Level

300

form

liquid

feature

SNAP-N-SPIKE®, SNAP-N-SHOOT®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

100 μg/mL in acetonitrile

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

SMILES string

C[C@]12CCC(=O)C=C1CC[C@H]3[C@@H]4CC[C@H](C(=O)CO)[C@]4(C[C@H](O)[C@H]23)C=O

InChI

1S/C21H28O5/c1-20-7-6-13(24)8-12(20)2-3-14-15-4-5-16(18(26)10-22)21(15,11-23)9-17(25)19(14)20/h8,11,14-17,19,22,25H,2-7,9-10H2,1H3/t14-,15-,16+,17-,19+,20-,21+/m0/s1

InChI key

PQSUYGKTWSAVDQ-ZVIOFETBSA-N

General description

Aldosterone is a hormone in the mineralocorticoid family which stimulates sodium transport across cell membranes and assists in the maintenance of blood pressure and blood volume. Aldosterone levels in serum/plasma and urine are measured by LC-MS/MS for investigation of primary or secondary aldosteronism ranging from adrenal cortical hyperplasia to renovascular disease and Bartter′s syndrome.

Application

The d-isomer of aldosterone is considered to be the biologically active isomer.

Other Notes

Exists as an equilibrium mixture of the aldehyde and the hemiacetal.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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This Item
A9477F612746148
Aldosterone solution 100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

Supelco

A-096

Aldosterone solution

Aldosterone ≥95% (HPLC)

Sigma-Aldrich

A9477

Aldosterone

Fludrocortisone acetate ≥98%

Sigma-Aldrich

F6127

Fludrocortisone acetate

Corticosterone VETRANAL®, analytical standard

Supelco

46148

Corticosterone

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

-

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

form

liquid

form

powder

form

powder

form

-

format

single component solution

format

-

format

-

format

neat

Quality Level

300

Quality Level

200

Quality Level

100

Quality Level

100

grade

certified reference material

grade

-

grade

-

grade

analytical standard

storage temp.

−20°C

storage temp.

room temp

storage temp.

room temp

storage temp.

-

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

35.6 °F - closed cup

flash_point_c

2 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Athina Markou et al.
The Journal of clinical endocrinology and metabolism, 98(4), 1409-1416 (2013-03-09)
Primary aldosteronism (PA) is an established cause of hypertension, whereas high-normal serum aldosterone levels have been linked to an increased risk for hypertension. We aimed to define the post-fludrocortisone-dexamethasone suppression test (FDST) normal cutoff values of aldosterone and the aldosterone
Ajay D Rao et al.
The American journal of cardiology, 112(1), 73-78 (2013-04-20)
Myocardial extracellular matrix expansion and reduced coronary flow reserve (CFR) occur in patients with type 2 diabetes mellitus without heart failure or coronary artery disease. Because aldosterone is implicated in the pathophysiology of cardiac fibrosis and vascular injury, the aim
Felix Beuschlein
European journal of endocrinology, 168(6), R85-R93 (2013-04-10)
Arterial hypertension is a major cardiovascular risk factor that affects between 10 and 40% of the population in industrialized countries. Primary aldosteronism (PA) is the most common form of secondary hypertension with an estimated prevalence of around 10% in referral
View All Related Papers

Global Trade Item Number

SKUGTIN
A-096-1ML04061833326336

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