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702153

Hydroxyapatite

nanoparticles, dispersion, 10 wt. % in H2O, <200 nm particle size (BET)

Synonym(s):

Calcium hydroxide phosphate, Calcium hydroxylapatite, Calcium hydroxyphosphate, Nano hydroxyapatatite, Pentacalcium hydroxide triphosphate

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About This Item

Linear Formula:
[Ca5(OH)(PO4)3]x
CAS Number:
Molecular Weight:
502.31
NACRES:
NA.23
PubChem Substance ID:
UNSPSC Code:
12352302
MDL number:
Form:
dispersion, nanoparticles
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Quality Level

form

dispersion, nanoparticles

contains

≤0.025 wt. % dispersant (non-metal based)

concentration

10 wt. % in H2O

surface area

14.3 m2/g , typical

particle size

<200 nm (BET)

pH

4-6

density

1.038 g/mL at 25 °C

SMILES string

[Ca++].[Ca++].[Ca++].[Ca++].O[Ca+].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O

InChI

1S/5Ca.3H3O4P.H2O/c;;;;;3*1-5(2,3)4;/h;;;;;3*(H3,1,2,3,4);1H2/q5*+2;;;;/p-10

InChI key

XYJRXVWERLGGKC-UHFFFAOYSA-D

General description

Hydroxyapatite(HAP) is an osteoconductive bioceramic material which has uniqueability to form direct bonds with living tissues. It can be easily prepared byvarious techniques such as sol-gel, hydrothermal, multiple emulsion, biomimeticdeposition, and electrodeposition.

Application

Hydroxyapatite can be used as:
  • An implant material for bone substitute due to its chemical similarity to the inorganic component of bone and osteo inductive properties.
  • A vehicle for gene and drug delivery because of its encapsulation capacity and affinity to several drugs and proteins.
  • A pH responsive particulate emulsifier.

Features and Benefits

  • Biocompatible
  • Osteoconductive
  • Stable under physiological conditions
  • High mechanical strength

Legal Information

Product of Engi-Mat Co.

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1 of 1

This Item
677418693863574791
form

dispersion, nanoparticles

form

nanopowder, solid

form

nanopowder, solid

form

solid

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

pH

4-6

pH

-

pH

-

pH

-

density

1.038 g/mL at 25 °C

density

-

density

-

density

-

surface area

14.3 m2/g , typical

surface area

>9.4 m2/g

surface area

10-15 m2/g , typical

surface area

-

particle size

<200 nm (BET)

particle size

<200 nm (BET)

particle size

<200 nm (BET)

particle size

-


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Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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Martin P Reichhardt et al.
Life science alliance, 3(4) (2020-02-27)
The scavenger receptor cysteine-rich (SRCR) family of proteins comprises more than 20 membrane-associated and secreted molecules. Characterised by the presence of one or more copies of the ∼110 amino-acid SRCR domain, this class of proteins have widespread functions as antimicrobial
Xi Chen et al.
The Journal of biological chemistry, 289(16), 11162-11174 (2014-03-13)
Calcium phosphate precipitates (CPPs) form complexes with DNA, which enter cells via endocytosis. Under this condition CPPs induce autophagy via the canonic autophagy machinery. Here we showed that CPP-induced autophagy was also dependent on endocytosis as the process was significantly
Tie Liu et al.
Bone, 56(1), 110-118 (2013-06-05)
As an alternative to an autologous bone graft, deproteinized bovine bone (DBB) is widely used in the clinical dentistry. Although DBB provides an osteoconductive scaffold, it is not capable of enhancing bone regeneration because it is not osteoinductive. In order



Global Trade Item Number

SKUGTIN
702153-25ML04061832820743

Questions

  1. What is the dispersant used?

    1 answer
    1. The dispersant used is based on polyphosphoric acid, and approximately 0.25 wt% of hydroxyapatite is used.

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