42867

Dextran sulfate sodium salt

M_r ~40,000

• Synonym(s): DSS Dextran Sulfate Sodium
• NACRES: NA.25
• UNSPSC Code: 12352201

Properties

• form: powder
• Quality Segment: 100
• mol wt: M_r ~40,000
• technique(s): tissue culture: suitable
• loss: ≤10% loss on drying
• color: white to off-white
• useful pH range: 6.0-8 (10 g/L)
• mp: (Decomposes on heating.)
• solubility: water: soluble
• suitability: suitable for component for culture media
• storage temp.: room temp

Description

General description

Dextran is a polymer of anhydroglucose. It is composed of approximately 95% alpha-D-(166) linkages. The remaining (163) linkages account for the branching of dextran.

Application

Dextran sulfate is routinely used for the selective precipitation of lipoproteins, probe hybridization membrane-immobilized DNA, the release of DNA from DNA-histone complexes, and the inhibition of RNA binding to ribosomes.

Biochem/physiol Actions

Treatment with dextran sulfate sodium triggers development of colitis in mice and rats by binding to medium-chain-length fatty acids present in the colon and inducing inflammation.

Other Notes

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable