49449

L-Glutamic acid

≥99.5% (NT), BioUltra

• Synonym(s): (S)-2-Aminopentanedioic acid, Glu
• Linear Formula: HO₂CCH₂CH₂CH(NH₂)CO₂H
• CAS Number: 56-86-0
• Molecular Weight: 147.13
• NACRES: NA.26
• PubChem Substance ID: 57651195
• eCl@ss: 32160406
• UNSPSC Code: 12352209
• EC Number: 200-293-7
• MDL number: MFCD00002634
• Beilstein/REAXYS Number: 1723801

Properties

• Product Name: L-Glutamic acid, BioUltra, ≥99.5% (NT)
• product line: BioUltra
• Quality Segment: 200
• assay: ≥99.5% (NT)
• form: powder
• optical activity: [α]20/D +31.5±1.0°, c = 5% in 5 M HCl
• impurities: insoluble matter, passes filter test, ≤0.5% foreign amino acids
• ign. residue: ≤0.05% (as SO₄)
• loss: ≤0.05% loss on drying, 20 °C (HV)
• color: white
• mp: 205 °C (dec.) (lit.)
• solubility: 1 M HCl: 1 M at 20 °C, clear, colorless
• density: 1.54 g/cm³ at 20 °C
• anion traces: chloride (Cl^-): ≤100 mg/kg, sulfate (SO₄^2-): ≤200 mg/kg
• cation traces: Al: ≤5 mg/kg, Ba: ≤5 mg/kg, Bi: ≤5 mg/kg, Ca: ≤200 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Li: ≤5 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Mo: ≤5 mg/kg, NH₄⁺: ≤100 mg/kg, Na: ≤200 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Sr: ≤5 mg/kg, Zn: ≤5 mg/kg
• λ: 1 M in 1 M HCl
• UV absorption: λ: 260 nm A_max: 0.1, λ: 280 nm A_max: 0.1
• application(s): cell analysis
• SMILES string: N[C@@H](CCC(O)=O)C(O)=O
• InChI: 1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1
• InChI key: WHUUTDBJXJRKMK-VKHMYHEASA-N
• Gene Information: human ... CCR2(1231), GRIA1(2890), GRIA2(2891), GRIA4(2893), GRIK1(2897), GRIK2(2898), GRIK3(2899), GRIK5(2901), GRIN2B(2904), GRM2(2912), SLC1A1(6505), SLC1A2(6506) ; rat ... Gria1(50592), Grik1(29559), Grik2(54257), Grik4(24406), Grin2a(24409), Grm1(24414), Grm2(24415), Grm3(24416), Grm4(24417), Grm5(24418), Grm6(24419), Grm7(81672), Slc1a2(29482)

Description

Biochem/physiol Actions

An excitatory amino acid neurotransmitter that is an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA).

Other Notes

Lesion-sparing agent, has excitotoxic properties[1]; May function as precipitating agent in protein crystallization[2]; Growth requirement of various microorganisms

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)