C2832

Cholesteryl 3β-N-(di­methyl­amino­ethyl)­carbamate hydrochloride

≥95%, Cholesterol derivative, powder

• Synonym(s): 3β-[N-(Dimethylaminoethane)­carbamoyl]­cholesterol, DC-Chol
• Empirical Formula (Hill Notation): C₃₂H₅₇ClN₂O₂
• CAS Number: 166023-21-8
• Molecular Weight: 537.26
• UNSPSC Code: 12352200
• PubChem Substance ID: 24892536
• NACRES: NA.77
• MDL number: MFCD00467173
• Assay: ≥95%
• Form: powder

Properties

• Product Name: Cholesteryl 3β-N-(di­methyl­amino­ethyl)­carbamate hydrochloride, ≥95%
• Quality Segment: 200
• assay: ≥95%
• form: powder
• storage temp.: −20°C
• SMILES string: Cl[H].[H][C@@]1(CC[C@@]2([H])[C@]3([H])CC=C4C[C@H](CC[C@]4(C)[C@@]3([H])CC[C@]12C)OC(=O)NCCN(C)C)[C@H](C)CCCC(C)C
• InChI: 1S/C32H56N2O2.ClH/c1-22(2)9-8-10-23(3)27-13-14-28-26-12-11-24-21-25(36-30(35)33-19-20-34(6)7)15-17-31(24,4)29(26)16-18-32(27,28)5;/h11,22-23,25-29H,8-10,12-21H2,1-7H3,(H,33,35);1H/t23-,25+,26+,27-,28+,29+,31+,32-;/m1./s1
• InChI key: ISXSJGHXHUZXNF-LXZPIJOJSA-N

Description

Application

This cationic cholesterol derivative forms liposomes with L-α-phosphatidylethanolamine, dioleoyl, that efficiently transfect mammalian cell lines.

Cholesteryl 3β-N-(di­methyl­amino­ethyl)­carbamate hydrochloride has been used as a bilayer-membrane stabiliser[1] and for nucleic acid transfer.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)