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77161

Pepsin from porcine gastric mucosa

tested according to Ph. Eur.

Synonym(s):

Pepsini pulvis, Pepsin A, Pepsin from hog stomach

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About This Item

CAS Number:
UNSPSC Code:
12352204
eCl@ss:
42010127
EC Number:
232-629-3
NACRES:
NA.54
MDL number:
EC Number:
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agency

tested according to Ph. Eur.

form

powder

mol wt

35 kDa

UniProt accession no.

storage temp.

2-8°C

Gene Information

Application

Pepsin cleavage can be used to produce F(ab′)2 fragments of antibodies. pepsin at www.sigma-aldrich.com/enzymeexplorer.

Biochem/physiol Actions

Preferential cleavage: hydrophobic and aromatic residues in P1 and P1′ postitions. Cleaves Phe-Val, Gln-His, Glu-Ala, Ala-Leu, Leu-Tyr, Tyr-Leu, Gly-Phe, Phe-Phe and Phe-Tyr bonds in the β chain of insulin

Analysis Note

Optimum pH is 2-4. Active in 4 M urea and 3 M guanidine HCl. Stable at 60 °C. Pepsin is irreversibly inactivated at pH 8.0 - 8.5.

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This Item
SRE000177151P7000
Gene Information

pig ... LOC396892(396892)

Gene Information

pig ... LOC396892(396892)

Gene Information

pig ... LOC396892(396892)

Gene Information

pig ... LOC396892(396892)

form

powder

form

lyophilized powder

form

powder

form

powder

UniProt accession no.

P00791

UniProt accession no.

P00791

UniProt accession no.

P00791

UniProt accession no.

P00791

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

2-8°C

mol wt

35 kDa

mol wt

35 kDa

mol wt

35 kDa

mol wt

35 kDa

agency

tested according to Ph. Eur.

agency

-

agency

-

agency

-


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pictograms

Health hazardExclamation mark

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves



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Questions

  1. Hi, How many U/mL is in this product?

    1 answer
    1. This product is a powder with a minimum activity specification of 0.5 Ph. Eur. U/mg (calculated on dry substance). Kindly review the lot-specific certificate of analysis for the lot-specific result.

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