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C-016

(−)-Cotinine solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C10H12N2O
CAS Number:
Molecular Weight:
176.22
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
200-659-6
MDL number:
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grade

certified reference material

Quality Segment

form

liquid

feature

SNAP-N-SPIKE®, SNAP-N-SHOOT®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

−20°C

SMILES string

CN1C(CCC1=O)c2cccnc2

InChI

1S/C10H12N2O/c1-12-9(4-5-10(12)13)8-3-2-6-11-7-8/h2-3,6-7,9H,4-5H2,1H3/t9-/m0/s1

InChI key

UIKROCXWUNQSPJ-VIFPVBQESA-N

General description

An analytical reference standard of the major urinary metabolite of nicotine. Not only is cotinine a biomarker for users of nicotine products including cigarettes, cigars, and snuff, but it′s also an alkaloid found in tobacco. Suitable uses for this analytical reference standard include as a starting material in calibrators and controls for GC/MS and LC/MS applications in nicotine testing methods or clinical and diagnostic testing of nicotine biomarkers.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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This Item
C0430H-108C-017
application(s)

forensics and toxicology

application(s)

environmental
pharmaceutical (small molecule)

application(s)

forensics and toxicology

application(s)

forensics and toxicology

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

form

liquid

form

-

form

liquid

form

liquid

Quality Level

300

Quality Level

100

Quality Level

300

Quality Level

300

grade

certified reference material

grade

drug standard

grade

certified reference material

grade

certified reference material

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C


signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup



Certificates of Analysis (COA)

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R R Watts et al.
Environmental health perspectives, 84, 173-182 (1990-03-01)
A two-day technical workshop was convened November 10-11, 1986, to discuss analytical approaches for determining trace amounts of cotinine in human body fluids resulting from passive exposure to environmental tobacco smoke (ETS). The workshop, jointly sponsored by the U.S. Environmental
Kuan-Yen Tung et al.
Environmental research, 124, 7-12 (2013-04-30)
Environmental tobacco smoke (ETS) is a hazardous component of indoor air, and may increase the risk of respiratory diseases, atherosclerosis and otitis media in children. In this study, we explored the relationship between time inside the house, ETS exposure and
Ines Moreno-Gonzalez et al.
Nature communications, 4, 1495-1495 (2013-02-21)
Several epidemiological studies have shown that cigarette smoking might alter the incidence of Alzheimer's disease. However, inconsistent results have been reported regarding the risk of Alzheimer's disease among smokers. Previous studies in experimental animal models have reported that administration of



Global Trade Item Number

SKUGTIN
C-016-1ML04061833444443

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