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D-Sorbitol

Name: <SC>D</SC>-Sorbitol
Brand: SIGMA

≥98% (GC), BioXtra

Synonym(s):

D-Glucitol

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About This Item

Empirical Formula (Hill Notation):

C₆H₁₄O₆

CAS Number:

50-70-4

Molecular Weight:

182.17

UNSPSC Code:

12352201

NACRES:

NA.25

PubChem Substance ID:

24899755

EC Number:

200-061-5

Beilstein/REAXYS Number:

1721899

MDL number:

MFCD00004708

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Properties

vapor density

<1 (vs air)

Quality Level

200

vapor pressure

<0.1 mmHg ( 25 °C)

product line

BioXtra

assay

≥98% (GC)

form

powder or chunks

impurities

<0.001% Phosphorus (P), <0.1% Insoluble matter

ign. residue

<0.1%

color

white

useful pH range

5.0-7.0 (25 °C, 182 g/L)

mp

98-100 °C (lit.)

solubility

H₂O: 1 M, clear, colorless (room temperature)

anion traces

chloride (Cl^-): <0.005%, sulfate (SO₄^2-): <0.01%

cation traces

Al: <0.0005%, Ca: <0.0005%, Cu: <0.0005%, Fe: <0.0005%, K: <0.005%, Mg: <0.0005%, NH₄⁺: <0.05%, Na: <0.005%, Pb: <0.001%, Zn: <0.0005%

SMILES string

OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CO

InChI

1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5-,6-/m1/s1

InChI key

FBPFZTCFMRRESA-JGWLITMVSA-N

Description

Application

May be used for washing spheroplasts[1] and in isoelectric focusing to minimize endoosmotic flow in agarose gels.[2] May be used to induce osmotic stress.

Biochem/physiol Actions

D-Sorbitol is a sugar alcohol that is commonly used as a sugar substitute. It occurs naturally and is also produced synthetically from glucose. The food industry uses D-sorbitol as an additive in the form of a sweetener, humectant, emulsifier, thickener, or dietary supplement. D-Sorbitol has also been found in cosmetics, paper, and pharmaceuticals. Naturally, D-sorbitol occurs widely in plants via photosynthesis, ranging from algae to higher order fruits of the family Rosaceae.

Other Notes

To gain a comprehensive understanding of our extensive range of Sugar alcohols for your research, we encourage you to visit our Carbohydrates Category page.

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This Item	S1876	240850	S6021
Sigma-Aldrich S7547 D-Sorbitol	Sigma-Aldrich S1876 D-Sorbitol	Sigma-Aldrich 240850 D-Sorbitol	Sigma-Aldrich S6021 D-Sorbitol
assay ≥98% (GC)	assay ≥98% (GC)	assay 99% (GC)	assay ≥98% (GC)
Quality Level 200	Quality Level 300	Quality Level 200	Quality Level 200
solubility H₂O: 1 M, clear, colorless (room temperature)	solubility water: 200 mg/mL, clear, colorless	solubility water: soluble 182 g/L at 20 °C (68 °F )	solubility water: soluble 182g/l at 20 °C (68 °F)
form powder or chunks	form powder or crystals	form powder	form powder or crystals
cation traces Al: <0.0005%, Cu: <0.0005%, K: <0.005%, NH₄⁺: <0.05%, Pb: <0.001%, Ca: <0.0005%, Mg: <0.0005%, Zn: <0.0005%, Fe: <0.0005%, Na: <0.005%	cation traces -	cation traces -	cation traces -
product line BioXtra	product line -	product line -	product line -

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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Isoelectric focusing.

D E Garfin

Methods in enzymology, 182, 459-477 (1990-01-01)

Tolrestat pharmacokinetic and pharmacodynamic effects on red blood cell sorbitol levels in normal volunteers and in patients with insulin-dependent diabetes.

J M van Griensven et al.

Clinical pharmacology and therapeutics, 58(6), 631-640 (1995-12-01)

To examine the effect of diabetes mellitus on the pharmacokinetics of tolrestat and to investigate its effect on red blood cell sorbitol levels according to a new pharmacodynamic model for this class of drugs. Single and multiple doses of tolrestat

Electrocatalytic hydrogenation and deoxygenation of glucose on solid metal electrodes.

Youngkook Kwon et al.

ChemSusChem, 6(3), 455-462 (2013-01-25)

This Full Paper addresses the electrocatalytic hydrogenation of glucose to sorbitol or 2-deoxysorbitol on solid metal electrodes in neutral media. Combining voltammetry and online product analysis with high-performance liquid chromatography (HPLC), provides both qualitative and quantitative information regarding the reaction

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Global Trade Item Number

SKU	GTIN
S7547-1KG	04061836960056
S7547-250G	04061836960063

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