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Menadione sodium bisulfite

Name: Menadione sodium bisulfite
Brand: SIGMA

BioReagent, suitable for cell culture, ≥95% (TLC)

Synonym(s):

2-Methyl-1,4-naphthoquinone sodium bisulfite

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About This Item

Empirical Formula (Hill Notation):

C₁₁H₉NaO₅S

CAS Number:

130-37-0

Molecular Weight:

276.24

NACRES:

NA.75

PubChem Substance ID:

24896741

UNSPSC Code:

12352205

EC Number:

204-987-0

MDL number:

MFCD00051456

Assay:

≥95% (TLC)

Form:

powder

Pricing and availability is not currently available.

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Properties

biological source

synthetic (organic)

Quality Segment

200

product line

BioReagent

assay

≥95% (TLC)

form

powder

mol wt

M_w 276.24 g/mol

technique(s)

cell culture | mammalian: suitable, cell culture | plant: suitable

color

white to off-white

solubility

water: soluble 50 mg/mL, clear, colorless to light yellow

storage temp.

−20°C

SMILES string

[Na+].CC1(CC(=O)c2ccccc2C1=O)S([O-])(=O)=O

InChI

1S/C11H10O5S.Na/c1-11(17(14,15)16)6-9(12)7-4-2-3-5-8(7)10(11)13;/h2-5H,6H2,1H3,(H,14,15,16);/q;+1/p-1

InChI key

XDPFHGWVCTXHDX-UHFFFAOYSA-M

Description

Application

Menadione sodium bisulfite has been used:

as a free radical inducer to study its effects on oxidative stress in sunflower seedlings
as a positive control to produce mitochondrial O₂ during the measurement of O₂ in human proximal tubular cell lines
as a redox-cycling mitochondrial pro-oxidant to study its effects on protein kinase B (AKT) and mechanistic target of rapamycin (mTOR) signaling in cardiac cells

Biochem/physiol Actions

Menadione sodium bisulfite (MSB) is a derivative of vitamin K3 and has been studied in the treatment of hemorrhagic diseases like hypoprothrombinemia and neonatal hemorrhage, caused due to vitamin K3 deficiency. It is also considered a nutritional supplement for animals. MSB shows anticancer effects. It also protects plants from biotic and abiotic stress.

Other Notes

Water soluble vitamin K₃.

Disclaimer

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

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This Item	1.06528	M5750	8.04240
Sigma-Aldrich M2518 Menadione sodium bisulfite	Supelco 1.06528 Sodium disulfite	Sigma-Aldrich M5750 Menadione sodium bisulfite	Sigma-Aldrich 8.04240 Glutardialdehyde bis (sodium hydrogen sulfite)
assay ≥95% (TLC)	assay 98.0-100.5% (iodometric)	assay ≥95% (TLC)	assay -
Quality Level 200	Quality Level 300	Quality Level 200	Quality Level 200
solubility water: soluble 50 mg/mL, clear, colorless to light yellow	solubility 650 g/L	solubility H₂O: ≥50 mg/mL, clear, colorless to faintly yellow	solubility 285 g/L
storage temp. −20°C	storage temp. 2-30°C	storage temp. −20°C	storage temp. 2-30°C
form powder	form powder	form powder	form powder
technique(s) cell culture \| mammalian: suitable, cell culture \| plant: suitable	technique(s) -	technique(s) -	technique(s) -