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G5386

Gly-Gly-Tyr-Arg

powder, ≥97% (HPLC)

Synonym(s):

GGYR, Glycyl-glycyl-tyrosyl-arginine

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About This Item

Empirical Formula (Hill Notation):
C19H29N7O6
CAS Number:
Molecular Weight:
451.48
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.83
MDL number:
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Product Name

Gly-Gly-Tyr-Arg, ≥97% (HPLC)

biological source

synthetic (organic)

Quality Level

assay

≥97% (HPLC)

form

powder

solubility

water: 2 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

NCC(=O)NCC(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CCCNC(N)=N)C(O)=O

InChI

1S/C19H29N7O6/c20-9-15(28)24-10-16(29)25-14(8-11-3-5-12(27)6-4-11)17(30)26-13(18(31)32)2-1-7-23-19(21)22/h3-6,13-14,27H,1-2,7-10,20H2,(H,24,28)(H,25,29)(H,26,30)(H,31,32)(H4,21,22,23)

InChI key

FJPHHBGPPJXISY-UHFFFAOYSA-N

Application

Gly-Gly-Tyr-Arg has been used:
  • in the synthesis of the dimethoxyphosphotyrosine adduct to determine if diethoxyphosphate tyrosine (depY), a monoclonal antibody could distinguish between dimethoxyphosphotyrosine and diethoxyphosphotyrosine[1]
  • to graft on to a soft polyacrylamide for sodium dodecyl sulfate–polyacrylamide gel electrophoresis (SDS-PAGE) to perform high-resolution separation of peptides[2]
  • as a model peptide to react with 3,3-dithiobis(sulfosuccinimidyl propionate) (DTSSP) to understand the chemistry of DTSSP and similar cross-linking reagents[3]


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This Item
G3502G3882A6677
assay

≥97% (HPLC)

assay

≥98% (TLC)

assay

≥98% (TLC)

assay

≥97% (HPLC)

biological source

synthetic (organic)

biological source

-

biological source

-

biological source

synthetic (organic
organic)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

powder

form

powder

form

powder

form

powder

solubility

water: 2 mg/mL, clear, colorless

solubility

-

solubility

-

solubility

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Catherine L Swaim et al.
Journal of the American Society for Mass Spectrometry, 15(5), 736-749 (2004-05-04)
Synthetic cross-linking reagents, such as 3,3'-dithiobis(sulfosuccinimidyl propionate), DTSSP, can react with sidechains of amino acids that are within close proximity. Identification of cross-linked residues provides insight into the folded structures of proteins. However, analysis of proteolytic digests of proteins cross-linked
A J Kettle
FEBS letters, 379(1), 103-106 (1996-01-22)
Hypochlorous acid chlorinates tyrosyl residues in small peptides to produce chlorotyrosine. Detection of chlorotyrosine has the potential to unequivocally identify the contribution hypochlorous acid makes to inflammation. I have developed a selective and sensitive HPLC assay for measuring chlorotyrosine. When
Xin Ying et al.
Food research international (Ottawa, Ont.), 141, 110148-110148 (2021-03-02)
Soy peptide solution (40%, w/w) was successfully encapsulated in a W1/O/W2 double emulsion produced by a two-step emulsification process. Polyglycerol polyricinoleate (PGPR) was found to be an effective inner emulsifier compared to Span 60 and lecithin to produce stable W1/O



Global Trade Item Number

SKUGTIN
G5386-100MG04061833261866

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